Evidence map›Paper›PMID 37239270›Full record

ArticleBrain sciences2023

Attachment Trauma Is Associated with White Matter Fiber Microstructural Alterations in Adolescents with Anorexia Nervosa before and after Exposure to Psychotherapeutic and Nutritional Treatment.

Manuela Gander, Lukas Lenhart, Ruth Steiger, Anna Buchheim, Stephanie Mangesius, Christoph Birkl, Nina Haid-Stecher, Martin Fuchs, Anna Libal, Agnieszka Dabkowska-Mika and 2 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Manuela GanderInstitute of Psychology, Leopold-Franzens-University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-9669-5561
Lukas LenhartDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-1716-1057
Ruth SteigerDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Anna BuchheimInstitute of Psychology, Leopold-Franzens-University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-1339-5246
Stephanie MangesiusDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0001-5790-2724
Christoph BirklDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0003-3101-4002
Nina Haid-StecherDepartment of Child and Adolescent Psychiatry, Tirol Kliniken, 6060 Hall in Tirol, Austria.
Martin FuchsDepartment of Child and Adolescent Psychiatry, Tirol Kliniken, 6060 Hall in Tirol, Austria.
Anna LibalDepartment of Child and Adolescent Psychiatry, Tirol Kliniken, 6060 Hall in Tirol, Austria.
Agnieszka Dabkowska-MikaDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Elke Ruth GizewskiDepartment of Neuroradiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Kathrin SeveckeDepartment of Child and Adolescent Psychiatry, Tirol Kliniken, 6060 Hall in Tirol, Austria.
Innsbruck Medical University · ATTirol Kliniken · ATUniversität Innsbruck · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, we explore the role of attachment for microstructural white matter (WM) changes in adolescents with anorexia nervosa (AN) before and after exposure to short-term and nutritional treatment. The case sample consisted of 22 female adolescent inpatients with AN (mean age: 15.2 ± 1.2 years) and the control sample were 18 gender-matched healthy adolescents (mean age: 16.8 ± 0.9 years). We performed a 3T MRI in the patient group during the acute state of AN and after weight restoration (duration: 2.6 ± 1 months) and compared the data to a healthy control group. To classify attachment patterns, we used the Adult Attachment Projective Picture System. In the patient sample, over 50% were classified with an attachment trauma/unresolved attachment status. Prior to treatment exposure, fractional anisotropy (FA) reductions and concordant mean diffusivity (MD) increases were evident in the fornix, the corpus callosum and WM regions of the thalamus, which normalized in the corpus callosum and the fornix post-therapy in the total patient sample (

Indexed as

adolescenceanorexia nervosaattachmentfractional anisotropywhite matter

Identifiers

PMID37239270
PMCPMC10216391
OpenAlexW4378515692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.