Evidence map›Paper›PMID 37239060›Full record

ArticleBiomedicines2023

Parnassin, a Novel Therapeutic Peptide, Alleviates Skin Lesions in a DNCB-Induced Atopic Dermatitis Mouse Model.

Jeon Hwang-Bo, Karpagam Veerappan, Hyunhye Moon, Tae-Hoon Lee, Kang-Woon Lee, Junhyung Park, Hoyong Chung

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

  1. AAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jeon Hwang-Bo3BIGS Co., Ltd., Hwaseong 18469, Republic of Korea.
Karpagam Veerappan3BIGS Co., Ltd., Hwaseong 18469, Republic of Korea.ORCID 0000-0002-9910-6715
Hyunhye Moon3BIGS Co., Ltd., Hwaseong 18469, Republic of Korea.ORCID 0009-0004-8700-2806
Tae-Hoon LeeDepartment of Applied Chemistry, Kyung Hee University, Yongin 17410, Republic of Korea.
Kang-Woon LeeHoloce Ecosystem Conservation Research Institute, Hweongsung 25257, Republic of Korea.
Junhyung Park3BIGS Co., Ltd., Hwaseong 18469, Republic of Korea.ORCID 0000-0002-0805-6362
Hoyong Chung3BIGS Co., Ltd., Hwaseong 18469, Republic of Korea.ORCID 0000-0002-1437-3559
Gyeongsangnam-do Agricultural Research and Extension Services · KRKyung Hee University · KR

Funding

3BIGS Research Fund 3BIGS-R-20200006
6 · The paper itself

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin disease which requires continuous treatment due to its relapsing nature. The current treatment includes steroids and nonsteroidal agents targeting inflammation but long-term administration causes various side effects such as skin atrophy, hirsutism, hypertension and diarrhea. Thus, there is an unmet need for safer and effective therapeutic agents in the treatment of AD. Peptides are small biomolecule drugs which are highly potent and remarkably have less side effects. Parnassin is a tetrapeptide with predicted anti-microbial activity curated from

Indexed as

atopic dermatitisparnassinParnassius bremeripeptide drugtranscriptome

Identifiers

PMID37239060
PMCPMC10216559
OpenAlexW4375862001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.