Evidence map›Paper›PMID 37238962›Full record

ArticleBiomedicines2023

Mechanisms Underlying the Suppression of IL-1β Expression by Magnesium Hydroxide Nanoparticles.

Ayaka Koga, Chuencheewit Thongsiri, Daisuke Kudo, Dao Nguyen Duy Phuong, Yoshihito Iwamoto, Wataru Fujii, Yoshie Nagai-Yoshioka, Ryota Yamasaki, Wataru Ariyoshi

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Ayaka KogaDepartment of Health Sciences, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.
Chuencheewit ThongsiriDepartment of Conservative Dentistry and Prosthodontics, Srinakharinwirot University, Bangkok 10110, Thailand.
Daisuke KudoSETOLAS Holdings Inc., Sakaide 762-0012, Kagawa, Japan.
Dao Nguyen Duy PhuongSETOLAS Holdings Inc., Sakaide 762-0012, Kagawa, Japan.
Yoshihito IwamotoSETOLAS Holdings Inc., Sakaide 762-0012, Kagawa, Japan.
Wataru FujiiUnit of Interdisciplinary Promotion, School of Oral Health Sciences, Faculty of Dentistry, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.ORCID 0000-0003-3417-4415
Yoshie Nagai-YoshiokaDivision of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.ORCID 0009-0004-2615-6545
Ryota YamasakiDivision of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.ORCID 0000-0003-1152-3248
Wataru AriyoshiDivision of Infections and Molecular Biology, Department of Health Promotion, Kyushu Dental University, Kitakyushu 803-8580, Fukuoka, Japan.ORCID 0000-0002-6533-5683
Kyushu Dental University · JPSrinakharinwirot University · TH

Funding

Japan Society for the Promotion of Science 21H03145Japan Society for the Promotion of Science 22K17020
6 · The paper itself

Abstract

In recent years, magnesium hydroxide has been widely studied due to its bioactivity and biocompatibility. The bactericidal effects of magnesium hydroxide nanoparticles on oral bacteria have also been reported. Therefore, in this study, we investigated the biological effects of magnesium hydroxide nanoparticles on inflammatory responses induced by periodontopathic bacteria. Macrophage-like cells, namely J774.1 cells, were treated with LPS derived from

Indexed as

dentistryinnate immunitymacrophagesmagnesium hydroxide nanoparticlesMAPK pathwaysNF-κB pathwaysperiodontology

Identifiers

PMID37238962
PMCPMC10215582
OpenAlexW4367319993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.