Evidence map›Paper›PMID 37238743›Full record

ReviewBiomolecules2023

The Potential of Edible and Medicinal Resource Polysaccharides for Prevention and Treatment of Neurodegenerative Diseases.

Qingxia Gan, Yugang Ding, Maoyao Peng, Linlin Chen, Jijing Dong, Jiaxi Hu, Yuntong Ma

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qingxia GanCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Yugang DingCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Maoyao PengCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Linlin ChenCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Jijing DongCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Jiaxi HuCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Yuntong MaCollege of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
State Administration of Traditional Chinese Medicine of the People's Republic of China · CNChengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As natural medicines in complementary and alternative medicine, edible and medicinal resources are being gradually recognized throughout the world. According to statistics from the World Health Organization, about 80% of the worldwide population has used edible and medicinal resource products to prevent and treat diseases. Polysaccharides, one of the main effective components in edible and medicinal resources, are considered ideal regulators of various biological responses due to their high effectiveness and low toxicity, and they have a wide range of possible applications for the development of functional foods for the regulation of common, frequently occurring, chronic and severe diseases. Such applications include the development of polysaccharide products for the prevention and treatment of neurodegenerative diseases that are difficult to control by a single treatment, which is of great value to the aging population. Therefore, we evaluated the potential of polysaccharides to prevent neurodegeneration by their regulation of behavioral and major pathologies, including abnormal protein aggregation and neuronal damage caused by neuronal apoptosis, autophagy, oxidative damage, neuroinflammation, unbalanced neurotransmitters, and poor synaptic plasticity. This includes multi-target and multi-pathway regulation involving the mitochondrial pathway, MAPK pathway, NF-κB pathway, Nrf2 pathway, mTOR pathway, PI3K/AKT pathway, P53/P21 pathway, and BDNF/TrkB/CREB pathway. In this paper, research into edible and medicinal resource polysaccharides for neurodegenerative diseases was reviewed in order to provide a basis for the development and application of polysaccharide health products and promote the recognition of functional products of edible and medicinal resources.

Indexed as

Neurodegenerative DiseasesAgedAgingHumansOxidative StressPhosphatidylinositol 3-KinasesPolysaccharidesPhosphatidylinositol 3-KinasesPolysaccharidesedible and medicinal resourceshealth productsneurodegenerative diseasespathwayspolysaccharides

Identifiers

PMID37238743
PMCPMC10216080
OpenAlexW4378083593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.