Evidence map›Paper›PMID 37238713›Full record

ArticleBiomolecules2023

Distribution of α

Chloé Laurencin, Sophie Lancelot, Inès Merida, Nicolas Costes, Jérôme Redouté, Didier Le Bars, Philippe Boulinguez, Bénédicte Ballanger

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03520543 (Positron Emission Tomography Study of alpha2-adrenergic Receptors With [11C]Yohimbine), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03520543 phase1completednot on this map

Positron Emission Tomography Study of alpha2-adrenergic Receptors With [11C]Yohimbine

TypeinterventionalSponsorHospices Civils de LyonRan2018 to 2019Enrolled16ConditionsHealthy ControlsArms[11C]Yohimbine, [11C]Yohimbine (Part B1) and [11C]Yohimbine + clonidine (Part B2)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. The role of αAmerican journal of physiology. Heart and circulatory physiology · 2025
    Article
  2. Article
  3. Central αThe Journal of physiology · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chloé LaurencinUniversité de Lyon, 69622 Lyon, France.
Sophie LancelotUniversité de Lyon, 69622 Lyon, France.
Inès MeridaCERMEP-Imagerie du Vivant, 69500 Bron, France.
Nicolas CostesCERMEP-Imagerie du Vivant, 69500 Bron, France.ORCID 0000-0002-2954-9262
Jérôme RedoutéCERMEP-Imagerie du Vivant, 69500 Bron, France.
Didier Le BarsCERMEP-Imagerie du Vivant, 69500 Bron, France.
Philippe BoulinguezUniversité de Lyon, 69622 Lyon, France.ORCID 0000-0003-3002-9501
Bénédicte BallangerUniversité de Lyon, 69622 Lyon, France.ORCID 0000-0002-1901-3501
Université Claude Bernard Lyon 1 · FRCentre d'Exploration et de Recherche Médicale par Emission de Positons · FRHospices Civils de Lyon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neurofunctional basis of the noradrenergic (NA) system and its associated disorders is still very incomplete because in vivo imaging tools in humans have been missing up to now. Here, for the first time, we use [

Indexed as

BrainReceptors, Adrenergic, alpha-2FemaleHumansMaleNorepinephrinePositron-Emission TomographyYohimbineNorepinephrineReceptors, Adrenergic, alpha-2Yohimbine[11C]yohimbinecartographyhumanhybrid PET/MRIin vivoα2-adrenoceptor

Identifiers

PMID37238713
PMCPMC10216046
OpenAlexW4376635911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.