Evidence map›Paper›PMID 37238678›Full record

ArticleBiomolecules2023

Generation of a Yeast Cell Model Potentially Useful to Identify the Mammalian Mitochondrial

Ruggiero Gorgoglione, Roberta Seccia, Amer Ahmed, Angelo Vozza, Loredana Capobianco, Alessia Lodi, Federica Marra, Eleonora Paradies, Luigi Palmieri, Vincenzo Coppola and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Aspartate-Glutamate Carrier 1 (International journal of molecular sciences · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Ruggiero GorgoglioneDepartment of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.
Roberta SecciaDepartment of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.
Amer AhmedDepartment of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.ORCID 0000-0002-0503-4045
Angelo VozzaDepartment of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.ORCID 0000-0002-2433-465X
Loredana CapobiancoDepartment of Biological and Environmental Sciences and Technologies, University of Salento, 73100 Lecce, Italy.ORCID 0000-0002-9058-7743
Alessia LodiDepartment of Nutritional Sciences, College of Natural Sciences, The University of Texas at Austin, Austin, TX 78712, USA.
Federica MarraDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.
Eleonora ParadiesCNR Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), 70125 Bari, Italy.
Luigi PalmieriDepartment of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.ORCID 0000-0002-6503-2922
Vincenzo CoppolaDepartment of Cancer Biology and Genetics, College of Medicine, The Ohio State University and Arthur G. James Comprehensive Cancer Center, Columbus, OH 43210, USA.ORCID 0000-0001-6163-1779
Vincenza DolceDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.ORCID 0000-0003-2966-4866
Giuseppe FiermonteDepartment of Bioscience, Biotechnology and Environment, University of Bari, 70125 Bari, Italy.ORCID 0000-0002-6764-9395
University of Bari Aldo Moro · ITUniversity of Calabria · ITDell Children's Medical Center of Central Texas · USInstitute of Biomembranes, Bioenergetics and Molecular Biotechnologies · ITThe Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute · USUniversity of Salento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human mitochondrial carrier family (MCF) consists of 53 members. Approximately one-fifth of them are still orphans of a function. Most mitochondrial transporters have been functionally characterized by reconstituting the bacterially expressed protein into liposomes and transport assays with radiolabeled compounds. The efficacy of this experimental approach is constrained to the commercial availability of the radiolabeled substrate to be used in the transport assays. A striking example is that of

Indexed as

Escherichia coliSaccharomyces cerevisiaeAnimalsArginineGlutamatesHumansMammalsOrnithineArginineGlutamatesN-acetylglutamic acidOrnithinemitochondrial carriersN-acetylglutamateurea cycleyeast cell model

Identifiers

PMID37238678
PMCPMC10216676
OpenAlexW4378515339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.