Evidence map›Paper›PMID 37238662›Full record

ArticleBiomolecules2023

Endotrophin Levels Are Associated with Allograft Outcomes in Kidney Transplant Recipients.

Nadja Sparding, Federica Genovese, Daniel Guldager Kring Rasmussen, Morten A Karsdal, Nicoline V Krogstrup, Marie Bodilsen Nielsen, Mads Hornum, Subagini Nagarajah, Henrik Birn, The Context Study Group and 3 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Nadja SpardingNordic Bioscience, 2730 Herlev, Denmark.ORCID 0000-0002-6979-0632
Federica GenoveseNordic Bioscience, 2730 Herlev, Denmark.ORCID 0000-0003-1984-1881
Daniel Guldager Kring RasmussenNordic Bioscience, 2730 Herlev, Denmark.ORCID 0000-0003-1642-7482
Morten A KarsdalNordic Bioscience, 2730 Herlev, Denmark.
Nicoline V KrogstrupDepartment of Renal Medicine, Aarhus University Hospital, 8200 Aarhus, Denmark.
Marie Bodilsen NielsenDepartment of Renal Medicine, Aarhus University Hospital, 8200 Aarhus, Denmark.
Mads HornumDepartment of Nephrology, Rigshospitalet and Department of Clinical Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.ORCID 0000-0002-0123-4007
Subagini NagarajahDepartment of Nephrology, Odense University Hospital, 5000 Odense, Denmark.
Henrik BirnDepartment of Renal Medicine, Aarhus University Hospital, 8200 Aarhus, Denmark.
The Context Study Group
Bente JespersenDepartment of Renal Medicine, Aarhus University Hospital, 8200 Aarhus, Denmark.ORCID 0000-0001-7196-2870
Martin TepelDepartment of Nephrology, Odense University Hospital, 5000 Odense, Denmark.
Rikke NørregaardDepartment of Clinical Medicine, Aarhus University, 8000 Aarhus, Denmark.ORCID 0000-0002-0580-373X
Aarhus University · DKNordic Bioscience (Denmark) · DKUniversity of Southern Denmark · DKUniversity of Copenhagen · DKAarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early prediction of kidney graft function may assist clinical management, and for this, reliable non-invasive biomarkers are needed. We evaluated endotrophin (ETP), a novel non-invasive biomarker of collagen type VI formation, as a prognostic marker in kidney transplant recipients. ETP levels were measured with the PRO-C6 ELISA in the plasma (P-ETP) of 218 and urine (U-ETP/Cr) of 172 kidney transplant recipients, one (D1) and five (D5) days, as well as three (M3) and twelve (M12) months, after transplantation. P-ETP and U-ETP/Cr at D1 (P-ETP AUC = 0.86,

Indexed as

Kidney TransplantationAllograftsCollagen Type VIDelayed Graft FunctionHumansPeptide FragmentsRisk FactorsTransplant RecipientsCollagen Type VIendotrophinPeptide Fragmentsbiomarkersdelayed graft functionfibrosiskidney failurekidney transplantation

Identifiers

PMID37238662
PMCPMC10216383
OpenAlexW4372286506

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.