Evidence map›Paper›PMID 37238622›Full record

ReviewBiomolecules2023

Update on Diabetic Kidney Disease (DKD): Focus on Non-Albuminuric DKD and Cardiovascular Risk.

Sabrina Scilletta, Maurizio Di Marco, Nicoletta Miano, Agnese Filippello, Stefania Di Mauro, Alessandra Scamporrino, Marco Musmeci, Giuseppe Coppolino, Francesco Di Giacomo Barbagallo, Giosiana Bosco and 4 more

Abstract readReview
In one paragraph

Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. [WD40 repeat-containing protein 6 aggravates diabetic kidney disease by promoting lipid accumulation in kidney].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sabrina ScillettaDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.ORCID 0009-0001-9061-0368
Maurizio Di MarcoDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.ORCID 0000-0001-9021-6101
Nicoletta MianoDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.ORCID 0000-0003-0429-9807
Agnese FilippelloDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.ORCID 0000-0001-6593-8823
Stefania Di MauroDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.ORCID 0000-0002-5436-8279
Alessandra ScamporrinoDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.ORCID 0000-0003-4483-3365
Marco MusmeciDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.
Giuseppe CoppolinoDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.
Francesco Di Giacomo BarbagalloDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.
Giosiana BoscoDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.ORCID 0009-0004-6036-927X
Roberto ScicaliDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.ORCID 0000-0002-7023-3649
Salvatore PiroDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.ORCID 0000-0002-1781-0902
Francesco PurrelloDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.
Antonino Di PinoDepartment of Clinical and Experimental Medicine, University of Catania, 95122 Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The classic description of diabetic kidney disease (DKD) involves progressive stages of glomerular hyperfiltration, microalbuminuria, proteinuria, and a decline in the estimated glomerular filtration rate (eGFR), leading to dialysis. In recent years, this concept has been increasingly challenged as evidence suggests that DKD presents more heterogeneously. Large studies have revealed that eGFR decline may also occur independently from the development of albuminuria. This concept led to the identification of a new DKD phenotype: non-albuminuric DKD (eGFR < 60 mL/min/1.73 m

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Diabetic NephropathiesRenal Insufficiency, ChronicAlbuminuriaHeart Disease Risk FactorsHumansRenal DialysisRisk Factorscardiovascular riskchronic complications of type 2 diabetesdiabetic kidney diseasenon-albuminuric diabetic kidney disease

Identifiers

PMID37238622
PMCPMC10216614

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.