Evidence map›Paper›PMID 37238374›Full record

ReviewChildren (Basel, Switzerland)2023

Short- and Long-Term Outcomes of Preeclampsia in Offspring: Review of the Literature.

Sevasti Koulouraki, Vasileios Paschos, Panagiota Pervanidou, Panagiotis Christopoulos, Angeliki Gerede, Makarios Eleftheriades

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Impact of maternal health on neonatal and long-term kidney outcomes.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  3. Article
  4. Hypertensive disorders of pregnancy and offspring's kidney health.Pediatric nephrology (Berlin, Germany) · 2026
    Article
  5. Article
  6. The pathophysiology of pre-eclampsia.Nature reviews. Nephrology · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Impacts of prenatal resiquimod exposure during late gestation on rat offspring development and behavior.American journal of physiology. Regulatory, integrative and comparative physiology · 2026
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sevasti KoulourakiSecond Department of Obstetrics and Gynaecology, Aretaieio Hospital, National and Kapodistrian University of Athens, 115 28 Athens, Greece.
Vasileios PaschosSecond Department of Obstetrics and Gynaecology, Aretaieio Hospital, National and Kapodistrian University of Athens, 115 28 Athens, Greece.
Panagiota PervanidouUnit of Developmental and Behavioral Pediatrics, First Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, 115 27 Athens, Greece.ORCID 0000-0002-6593-6489
Panagiotis ChristopoulosSecond Department of Obstetrics and Gynaecology, Aretaieio Hospital, National and Kapodistrian University of Athens, 115 28 Athens, Greece.ORCID 0000-0003-4112-8396
Angeliki GeredeDepartment of Obstetrics and Gynecology, Democritus University of Thrace, 691 00 Campus, Greece.ORCID 0000-0001-9296-3688
Makarios EleftheriadesSecond Department of Obstetrics and Gynaecology, Aretaieio Hospital, National and Kapodistrian University of Athens, 115 28 Athens, Greece.ORCID 0000-0003-4967-2505

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preeclampsia is a multisystemic clinical syndrome characterized by the appearance of new-onset hypertension and proteinuria or hypertension and end organ dysfunction even without proteinuria after 20 weeks of pregnancy or postpartum. Residing at the severe end of the spectrum of the hypertensive disorders of pregnancy, preeclampsia occurs in 3 to 8% of pregnancies worldwide and is a major cause of maternal and perinatal morbidity and mortality, accounting for 8-10% of all preterm births. The mechanism whereby preeclampsia increases the risk of the neurodevelopmental, cardiovascular, and metabolic morbidity of the mother's offspring is not well known, but it is possible that the preeclamptic environment induces epigenetic changes that adversely affect developmental plasticity. These developmental changes are crucial for optimal fetal growth and survival but may lead to an increased risk of chronic morbidity in childhood and even later in life. The aim of this review is to summarize both the short- and long-term effects of preeclampsia on offspring based on the current literature.

Indexed as

endocrine morbidityfetal cardiac remodelinghigh blood pressurenecrotizing enterocolitisneonatal RDSneonatal sepsisneurodevelopmentobesityoffspringpreeclampsia

Identifiers

PMID37238374
PMCPMC10216976

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.