Evidence map›Paper›PMID 37238352›Full record

ReviewChildren (Basel, Switzerland)2023

Ultra-Processed Food, Reward System and Childhood Obesity.

Valeria Calcaterra, Hellas Cena, Virginia Rossi, Sara Santero, Alice Bianchi, Gianvincenzo Zuccotti

Open access · goldAbstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
23.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Food-Related Attentional Biases in Restrained Eaters: A Meta-Analysis.The International journal of eating disorders · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Development and Validation of a New Tool for Assessing the Intake of Ultra-Processed Foods in Adult Population: GR-UPFAST.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Valeria CalcaterraDepartment of Internal Medicine and Therapeutics, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-2137-5974
Hellas CenaLaboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-5752-6199
Virginia RossiPediatric Department, Buzzi Children's Hospital, 20154 Milano, Italy.ORCID 0000-0001-8363-9210
Sara SanteroLaboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0009-0004-2125-4699
Alice BianchiPediatric Department, Buzzi Children's Hospital, 20154 Milano, Italy.
Gianvincenzo ZuccottiPediatric Department, Buzzi Children's Hospital, 20154 Milano, Italy.ORCID 0000-0002-2795-9874
University of Pavia · ITOspedale dei Bambini Vittore Buzzi · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity and overweight are a major public health problem globally. Diet quality is critical for proper child development, and an unhealthy diet is a preventable risk factor for noncommunicable diseases (NCDs), such as obesity. Consumption of sugar-sweetened beverages and ultra-processed foods (UPFs) in childhood may increase the BMI/BMI z-score, body fat percentage, or likelihood of overweight. A strict feeding regulation system allows for sufficient food to be consumed to meet ongoing metabolic demands while avoiding overconsumption. This narrative review explores the issues of obesity and the regulation of food intake related to reward systems and UPF consumption. Nutrient composition alone cannot explain the influence of UPFs on the risk of obesity. Furthermore, the non-nutritional properties of UPFs may explain the mechanisms underlying the relationship with obesity and NCDs. UPFs are designed to be highly palatable, appealing, and energy dense with a unique combination of the main taste enhancer ingredients to generate a strong rewarding stimulus and influence the circuits related to feeding facilitation. How individual UPF ingredients influence eating behavior and reward processes remains not fully elucidated. To increase the knowledge on the relationship between UPFs and pediatric obesity, it may be useful to limit the rapid growth in the prevalence of obesity and subsequent related complications, and to develop new strategies for appropriate food and nutrition policies.

Indexed as

adolescentsbrain reward systemchildrenfeeding regulationnutrients intakeobesityultra-processed foodunhealthy dietary pattern

Identifiers

PMID37238352
PMCPMC10217200
OpenAlexW4367624806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.