Evidence map›Paper›PMID 37238350›Full record

ArticleChildren (Basel, Switzerland)2023

Mannitol Challenge to Assess Therapy Response in Asthmatic Children: An Interventional Cohort Study.

Nikolaos Karantaglis, Fotios Kirvassilis, Elpis Hatziagorou, Antonios Gkantaras, Kalliopi Kontouli, John Tsanakas, Maria Emporiadou

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nikolaos KarantaglisPediatric Pulmonology and Cystic Fibrosis Unit, 3rd Pediatric Department, Aristotle University of Thessaloniki, Hippokration General Hospital of Thessaloniki, Konstantinoupoleos Str. 49, 54642 Thessaloniki, Greece.ORCID 0000-0002-7539-8426
Fotios KirvassilisPediatric Pulmonology and Cystic Fibrosis Unit, 3rd Pediatric Department, Aristotle University of Thessaloniki, Hippokration General Hospital of Thessaloniki, Konstantinoupoleos Str. 49, 54642 Thessaloniki, Greece.
Elpis HatziagorouPediatric Pulmonology and Cystic Fibrosis Unit, 3rd Pediatric Department, Aristotle University of Thessaloniki, Hippokration General Hospital of Thessaloniki, Konstantinoupoleos Str. 49, 54642 Thessaloniki, Greece.ORCID 0000-0001-9505-2054
Antonios GkantarasPediatric Immunology and Rheumatology Referral Center, 1st Department of Pediatrics, Aristotle University of Thessaloniki, Hippokration General Hospital of Thessaloniki, Konstantinoupoleos Str. 49, 54642 Thessaloniki, Greece.ORCID 0000-0003-3609-1824
Kalliopi KontouliPediatric Pulmonology and Cystic Fibrosis Unit, 3rd Pediatric Department, Aristotle University of Thessaloniki, Hippokration General Hospital of Thessaloniki, Konstantinoupoleos Str. 49, 54642 Thessaloniki, Greece.
John TsanakasPediatric Pulmonology and Cystic Fibrosis Unit, 3rd Pediatric Department, Aristotle University of Thessaloniki, Hippokration General Hospital of Thessaloniki, Konstantinoupoleos Str. 49, 54642 Thessaloniki, Greece.
Maria EmporiadouSchool of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Aristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchial provocation tests, such as the mannitol challenge, can be performed to identify and quantify the severity of bronchial hyperresponsiveness in asthmatic patients. Studies of the mannitol challenge as a monitoring tool in asthmatic children are limited. Our primary aim was to compare the bronchial hyperresponsiveness to mannitol in treatment-naive asthmatic children between baseline and three months after receiving the indicated asthma prophylaxis. Twenty-three asthmatic patients aged 4-16 years were analyzed in this prospective cohort study. All subjects underwent the mannitol challenge at baseline and after three months of treatment with budesonide ± formoterol. The difference in the provocative dose of mannitol to induce a 15% drop in FEV

Indexed as

asthma prophylaxisbronchial hyperresponsivenessbronchial provocation testsmannitol challengepediatric asthma

Identifiers

PMID37238350
PMCPMC10217717
OpenAlexW4367627523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.