Evidence map›Paper›PMID 37238219›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Preliminary Report on Optical Coherence Tomography Angiography Biomarkers in Non-Responders and Responders to Intravitreal Anti-VEGF Injection for Diabetic Macular Oedema.

Sanjana Chouhan, Rekha Priya Kalluri Bharat, Janani Surya, Sashwanthi Mohan, Janarthanam Jothi Balaji, V K Viekash, Vasudevan Lakshminarayanan, Rajiv Raman

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sanjana ChouhanShri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai 600006, India.ORCID 0000-0001-8016-2138
Rekha Priya Kalluri BharatShri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai 600006, India.
Janani SuryaShri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai 600006, India.
Sashwanthi MohanShri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai 600006, India.ORCID 0000-0002-2239-5440
Janarthanam Jothi BalajiDepartment of Optometry, Medical Research Foundation, Chennai 600040, India.ORCID 0000-0003-4138-9334
V K ViekashDepartment of Instrumentation and Control Engineering, National Institute of Technology, Tiruchirappalli 620015, India.ORCID 0000-0001-9313-7038
Vasudevan LakshminarayananTheoretical and Experimental Epistemology Lab, School of Optometry and Vision Science, University of Waterloo, Waterloo, ON N2L 3G1, Canada.ORCID 0000-0002-3473-1245
Rajiv RamanShri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai 600006, India.
Sankara Nethralaya · INNational Institute of Technology Tiruchirappalli · INUniversity of Waterloo · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify optical coherence tomography angiography (OCTA) biomarkers in patients who were treated for diabetic macular oedema (DME) with intravitreal anti-vascular endothelial growth factor (VEGF) injections and compare the OCTA parameters between responders and non-responders.

methodsA retrospective cohort study of 61 eyes with DME who received at least one intravitreal anti-VEGF injection was included between July 2017 and October 2020. The subjects underwent a comprehensive eye examination followed by an OCTA examination before and after intravitreal anti-VEGF injection. Demographic data, visual acuity, and OCTA parameters were documented, and further analysis was performed pre- and post-intravitreal anti-VEGF injection.

resultsOut of 61 eyes which underwent intravitreal anti-VEGF injection for diabetic macular oedema, 30 were responders (group 1) and 31 were non-responders (group 2). We found that the responders (group 1) had a higher vessel density in the outer ring that was statistically significant (

conclusionThe evaluation of SCP in OCTA in addition to DCP can result in a better prediction of treatment response and early management in diabetic macular oedema.

Indexed as

anti-vascular endothelial growth factor (VEGF) injectionbiomarkersdiabetic macular oedema (DME)optical coherence tomography angiography (OCTA)

Identifiers

PMID37238219
PMCPMC10216932
OpenAlexW4378515279

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.