Evidence map›Paper›PMID 37238180›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Deep versus Handcrafted Tensor Radiomics Features: Prediction of Survival in Head and Neck Cancer Using Machine Learning and Fusion Techniques.

Mohammad R Salmanpour, Seyed Masoud Rezaeijo, Mahdi Hosseinzadeh, Arman Rahmim

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammad R SalmanpourDepartment of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada.ORCID 0000-0002-9515-789X
Seyed Masoud RezaeijoDepartment of Medical Physics, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz 6135715794, Iran.
Mahdi HosseinzadehTechnological Virtual Collaboration (TECVICO CORP.), Vancouver, BC V5E 3J7, Canada.
Arman RahmimDepartment of Integrative Oncology, BC Cancer Research Institute, Vancouver, BC V5Z 1L3, Canada.ORCID 0000-0002-9980-2403

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough handcrafted radiomics features (RF) are commonly extracted via radiomics software, employing deep features (DF) extracted from deep learning (DL) algorithms merits significant investigation. Moreover, a "tensor'' radiomics paradigm where various flavours of a given feature are generated and explored can provide added value. We aimed to employ conventional and tensor DFs, and compare their outcome prediction performance to conventional and tensor RFs.

methods408 patients with head and neck cancer were selected from TCIA. PET images were first registered to CT, enhanced, normalized, and cropped. We employed 15 image-level fusion techniques (e.g., dual tree complex wavelet transform (DTCWT)) to combine PET and CT images. Subsequently, 215 RFs were extracted from each tumor in 17 images (or flavours) including CT only, PET only, and 15 fused PET-CT images through the standardized-SERA radiomics software. Furthermore, a 3 dimensional autoencoder was used to extract DFs. To predict the binary progression-free-survival-outcome, first, an end-to-end CNN algorithm was employed. Subsequently, we applied conventional and tensor DFs vs. RFs as extracted from each image to three sole classifiers, namely multilayer perceptron (MLP), random-forest, and logistic regression (LR), linked with dimension reduction algorithms.

resultsDTCWT fusion linked with CNN resulted in accuracies of 75.6 ± 7.0% and 63.4 ± 6.7% in five-fold cross-validation and external-nested-testing, respectively. For the tensor RF-framework, polynomial transform algorithms + analysis of variance feature selector (ANOVA) + LR enabled 76.67 ± 3.3% and 70.6 ± 6.7% in the mentioned tests. For the tensor DF framework, PCA + ANOVA + MLP arrived at 87.0 ± 3.5% and 85.3 ± 5.2% in both tests.

conclusionsThis study showed that tensor DF combined with proper machine learning approaches enhanced survival prediction performance compared to conventional DF, tensor and conventional RF, and end-to-end CNN frameworks.

Indexed as

deep learning algorithmsdeep learning featureshead and neck squamous cell carcinomashybrid machine learning methodsprogression-free survivalradiomic features

Identifiers

PMID37238180
PMCPMC10217462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.