Evidence map›Paper›PMID 37238095›Full record

ArticleAnimals : an open access journal from MDPI2023

Leucoderma in Buffaloes (

José Diomedes Barbosa, Bruno Igor de Oliveira Possidonio, Janayna Barroso Dos Santos, Hanna Gabriela da Silva Oliveira, Ananda Iara de Jesus Sousa, Camila Cordeiro Barbosa, Edsel Alves Beuttemmuller, Natália da Silva E Silva Silveira, Marilene Farias Brito, Felipe Masiero Salvarani

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Pathogens (Basel, Switzerland) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

José Diomedes BarbosaInstituto de Medicina Veterinária, Universidade Federal do Pará, Castanhal 68740-970, PA, Brazil.
Bruno Igor de Oliveira PossidonioInstituto de Medicina Veterinária, Universidade Federal do Pará, Castanhal 68740-970, PA, Brazil.ORCID 0000-0003-3844-3918
Janayna Barroso Dos SantosInstituto de Medicina Veterinária, Universidade Federal do Pará, Castanhal 68740-970, PA, Brazil.
Hanna Gabriela da Silva OliveiraInstituto de Medicina Veterinária, Universidade Federal do Pará, Castanhal 68740-970, PA, Brazil.ORCID 0000-0003-2222-0680
Ananda Iara de Jesus SousaInstituto de Medicina Veterinária, Universidade Federal do Pará, Castanhal 68740-970, PA, Brazil.
Camila Cordeiro BarbosaInstituto de Medicina Veterinária, Universidade Federal do Pará, Castanhal 68740-970, PA, Brazil.
Edsel Alves BeuttemmullerDepartamento de Epidemiologia e Saúde Pública (DESP), Instituto de Veterinária (IV), Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica 23890-000, RJ, Brazil.
Natália da Silva E Silva SilveiraInstituto de Medicina Veterinária, Universidade Federal do Pará, Castanhal 68740-970, PA, Brazil.
Marilene Farias BritoDepartamento de Epidemiologia e Saúde Pública (DESP), Instituto de Veterinária (IV), Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica 23890-000, RJ, Brazil.
Felipe Masiero SalvaraniInstituto de Medicina Veterinária, Universidade Federal do Pará, Castanhal 68740-970, PA, Brazil.ORCID 0000-0002-7711-6437
Universidade Federal do Pará · BRUniversidade Federal Rural do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leucoderma is a condition that affects the skin and hair of animals, causing depigmentation and acromotrichia. In buffaloes, this condition results in significant economic losses for the production chain due to its impact on the leather trade. This study aimed to investigate the epidemiological and clinicopathological aspects of leucoderma in buffaloes in the Amazon biome and describe the prophylactic treatment to control the disease. The study included 40 buffaloes, 16 males and 24 females, aged between 1 and 10 years, and were of the Murrah, Jafarabadi, Mediterranean, and Murrah × Mediterranean crossbreed breeds. The animals were raised without mineral supplementation. The clinical signs observed in the animals included acromotrichia and depigmentation, with varying degrees and distribution of skin lesions. Histological examination of the epidermis showed interrupted melanin production, mild dermal fibrosis, mild perivascular mononuclear inflammatory infiltrate, and pigmentary incontinence. None of the animals had the genotype for albinism. After 120 days of mineral supplementation based on the use of copper sulfate, the clinical signs of leucoderma regressed. There was no predisposition by breed, sex, or age for the occurrence of the disease. The regression of skin lesions after proper mineral supplementation suggests that copper deficiency may be considered an important factor for the occurrence of leucoderma in buffaloes in the Amazon biome.

Indexed as

acromotrichiaalbinismcopperleathermelaninskin depigmentationvitiligo

Identifiers

PMID37238095
PMCPMC10215957
OpenAlexW4377104068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.