Evidence map›Paper›PMID 37237961›Full record

ReviewAntioxidants (Basel, Switzerland)2023

Protective Roles of Hydrogen Sulfide in Alzheimer's Disease and Traumatic Brain Injury.

Bindu D Paul, Andrew A Pieper

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. The Role of Hydrogen Sulfide (HInternational journal of molecular sciences · 2023
    Pooled it
  4. Review
  5. Article
  6. Review
  7. HBiochemistry · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Cystathionine γ-lyase is a major regulator of cognitive function through neurotrophin signaling and neurogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Novel neurotherapeutic targets for substance use disorders: Neuroplasticity, neuroinflammation, gasotransmitters and non-canonical organ systems.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  13. Black gas, bright future: HNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  14. Review
  15. Intersection of HNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  16. Targeting macro- and micro-nutrient regulation of HNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  17. Gasotransmitter signaling in the brain: New frontiers for therapeutics.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  18. Article
  19. Hydrogen Sulfide (HInternational journal of molecular sciences · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Bindu D PaulDepartment of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-1862-6103
Andrew A PieperBrain Health Medicines Center, Harrington Discovery Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.
Johns Hopkins University · USUniversity Hospitals Cleveland Medical Center · US

Funding

Translational and Therapeutics CoreP30AG072959 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI Jonathan L Haines · 2021 to 2026
$23.9M
Thorase Regulation of the Actions of CocaineP50DA044123 · NIDA · JOHNS HOPKINS UNIVERSITY · PI DAWSON, VALINA L., JANAK, PATRICIA H. · 2018 to 2022
$9.0M
Chemical, Structural and Cell-Signaling Interrogation of 15-Prostanglandin Dehydrogenase in Tissue Repair and RegenerationRM1GM142002 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI MARKOWITZ, SANFORD D., PIEPER, ANDREW A · 2021 to 2025
$6.9M
Translational Therapeutics CoreP30AG062428 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI LEVERENZ, JAMES BRUCE · 2019 to 2020
$5.0M
Endophenotype Network-based Approaches to Prediction and Population-based Validation of In Silico Drug Repurposing for Alzheimer's DiseaseR01AG066707 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI Feixiong Cheng · 2020 to 2026
$4.9M
Alzheimer's MultiOme Data Repurposing: Artificial Intelligence, Network Medicine, and Therapeutics DiscoveryU01AG073323 · NIA · CLEVELAND CLINIC LERNER COM-CWRU · PI BEKRIS, LYNN, CHENG, FEIXIONG · 2021 to 2025
$4.0M
Neuroprotective actions of cystathionine g-lyase through gasotransmitter hydrogen sulfide signalingR01AG071512 · NIA · JOHNS HOPKINS UNIVERSITY · PI Bindu Paul · 2022 to 2026
$3.4M
Role of sulfhydration on the functions of the microtubule associated protein, TauR21AG073684 · NIA · JOHNS HOPKINS UNIVERSITY · PI PAUL, BINDU · 2021 to 2022
$450k
BLRD VA I01 BX005976NIA NIH HHS 1 U01 AG073323NIA NIH HHS P30 AG072959NIA NIH HHS P30 AGO62428-01NIA NIH HHS R01 AG066707NIA NIH HHS R01 AG071512NIA NIH HHS R01AG071512NIA NIH HHS R21 AG073684NIA NIH HHS R21AG073684NIA NIH HHS RO1AG066707NIA NIH HHS U01 AG073323NIDA NIH HHS P50 DA044123
6 · The paper itself

Abstract

The gaseous signaling molecule hydrogen sulfide (H

Indexed as

Alzheimer’s diseasecysteinedementiaHuntington’s diseasehydrogen sulfidelearning and memorymitochondrianeuroprotectiontranssulfurationtraumatic brain injury

Identifiers

PMID37237961
PMCPMC10215281
OpenAlexW4378515203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.