Evidence map›Paper›PMID 37237863›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Maternal and Neonatal Factors Modulating Breast Milk Cytokines in the First Month of Lactation.

David Ramiro-Cortijo, Gloria Herranz Carrillo, Pratibha Singh, Miguel Rebollo-Hernanz, Pilar Rodríguez-Rodríguez, Santiago Ruvira, María Martín-Trueba, Camilia R Martin, Silvia M Arribas

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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  9. Dermoscopy and reflectance confocal microscopy finding of different anatomic sites of Langerhans cell histiocytosis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

David Ramiro-CortijoDepartment of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.ORCID 0000-0001-7442-1586
Gloria Herranz CarrilloDivision of Neonatology, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, 28040 Madrid, Spain.
Pratibha SinghDivision of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.ORCID 0000-0002-6919-8479
Miguel Rebollo-HernanzDepartment of Agricultural Chemistry and Food Science, Institute of Food Science Research CIAL (UAM-CSIC), Universidad Autónoma de Madrid, 28049 Madrid, Spain.ORCID 0000-0003-1034-1290
Pilar Rodríguez-RodríguezDepartment of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.
Santiago RuviraDepartment of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.
María Martín-TruebaDepartment of Agricultural Chemistry and Food Science, Institute of Food Science Research CIAL (UAM-CSIC), Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Camilia R MartinDepartment of Neonatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Silvia M ArribasDepartment of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.
Beth Israel Deaconess Medical Center · USUniversidad Autónoma de Madrid · ESInstituto de Investigación en Ciencias de la Alimentación · ESInstituto de Investigación Sanitaria del Hospital Clínico San Carlos · ES

Funding

Instituto de la Mujer, Ministerio de Igualdad (Spain) PAC22-20/2ACT/22Promotion of Knowledge Transfer program from Universidad Autónoma de Madrid (Spain) PTC-2020
6 · The paper itself

Abstract

Breast milk (BM) cytokines support and modulate infant immunity, being particularly relevant in premature neonates with adverse outcomes (NAO). This study aimed to examine, in a cohort of Spanish breastfeeding women, changes in BM cytokines in the first month of lactation, their modulation by neonatal factors (sex, gestational age, and NAO), maternal factors (obstetric complications, C-section, and diet), and their relationship with oxidative status. Sixty-three mother-neonate dyads were studied at days 7 and 28 of lactation. Dietary habits were assessed by a 72-h dietary recall, and the maternal dietary inflammatory index (mDII) was calculated. BM cytokines (IL-10, IL-13, IL-8, MCP-1, and TNFα) were assessed by ultra-sensitive chemiluminescence. Total antioxidant capacity was assessed by the ABTS method and lipid peroxidation by the MDA+HNE kit. From days 7 to 28 of lactation, the levels of IL-10 and TNFα remained stable, while IL-13 increased (β = 0.85 ± 0.12,

Indexed as

breast milkcytokinesinflammatory dietlipid peroxidationneonatal adverse outcomeprematuritysextotal antioxidant capacity

Identifiers

PMID37237863
PMCPMC10215605
OpenAlexW4367055280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.