Evidence map›Paper›PMID 37237827›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Cytotoxicity and Antibiofilm Activity of Silver-Polypropylene Nanocomposites.

Denise Bellisario, Loredana Santo, Fabrizio Quadrini, Maryam Hassiba, Nour Bader, Shazeda H Chowdhury, Mohammad K Hassan, Susu M Zughaier

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Pharmaceutics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Denise BellisarioFaculty of Economics, Universitas Mercatorum, 00186 Rome, Italy.ORCID 0000-0001-5588-8738
Loredana SantoDepartment of Industrial Engineering, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-3340-491X
Fabrizio QuadriniDepartment of Industrial Engineering, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-1005-6716
Maryam HassibaCollege of Medicine, QU Health, Qatar University, Doha 2713, Qatar.
Nour BaderCenter for Advanced Materials, Qatar University, Doha 2713, Qatar.
Shazeda H ChowdhuryCollege of Medicine, QU Health, Qatar University, Doha 2713, Qatar.
Mohammad K HassanCenter for Advanced Materials, Qatar University, Doha 2713, Qatar.ORCID 0000-0002-5316-2463
Susu M ZughaierCollege of Medicine, QU Health, Qatar University, Doha 2713, Qatar.ORCID 0000-0001-7487-8770

Funding

Qatar University IRCC-2022 -563
6 · The paper itself

Abstract

The development of biocompatible nanomaterials that interface with human skin and tissue is critical for advancing prosthetics and other therapeutic medical needs. In this perspective, the development of nanoparticles with cytotoxicity and antibiofilm properties and biocompatibility characteristics are important. Metallic silver (Ag) exhibits good biocompatibility, but it is often challenging to integrate it into a nanocomposite without compromising its antibiofilm properties for optimal applications. In this study, new polymer nanocomposites (PNCs) with ultra-low filling content (0.0023-0.046 wt%) of Ag nanoplates were manufactured and tested. The cytotoxicity and antibiofilm activity of different composites with polypropylene (PP) matrix were examined. At first, PNCs surface were analyzed by means of AFM (atomic force microscopy) with phase contrast evaluation and FTIR (Fourier-transform infrared spectroscopy) to study the Ag nanoplates distribution. Subsequently, the cytotoxicity and growth properties of biofilms were assessed by MTT assay protocol and detection of nitric oxide radicals. Antibacterial and antibiofilm activities were measured against Gram-positive bacteria (

Indexed as

Ag nanocompositesantibiofilm activitycells viability measurementmetallic silver nanoplates

Identifiers

PMID37237827
PMCPMC10215392

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.