Evidence map›Paper›PMID 37237696›Full record

ArticleBioengineering (Basel, Switzerland)2023

Computational Modeling of Diffusion-Based Delamination for Active Implantable Medical Devices.

Minh-Hai Nguyen, Adrian Onken, Anika Wulff, Katharina Foremny, Patricia Torgau, Helmut Schütte, Sabine Hild, Theodor Doll

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Minh-Hai NguyenDepartment of Otolaryngology and Cluster of Excellence "Hearing4all", Hannover Medical School MHH, 30625 Hannover, Germany.ORCID 0009-0009-4175-3002
Adrian OnkenDepartment of Otolaryngology and Cluster of Excellence "Hearing4all", Hannover Medical School MHH, 30625 Hannover, Germany.
Anika WulffDepartment of Otolaryngology, Hannover Medical School MHH, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Katharina ForemnyDepartment of Otolaryngology, Hannover Medical School MHH, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Patricia TorgauDepartment of Otolaryngology, Hannover Medical School MHH, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Helmut SchütteDepartment of Engineering, Jade University of Applied Sciences, 26382 Wilhelmshaven, Germany.
Sabine HildInstitute of Polymer Chemistry, Johannes Kepler University, 4010 Linz, Austria.ORCID 0000-0001-6099-1924
Theodor DollDepartment of Otolaryngology and Cluster of Excellence "Hearing4all", Hannover Medical School MHH, 30625 Hannover, Germany.

Funding

H4A EXC2077Medical Device Obligations Taskforce 814654
6 · The paper itself

Abstract

Delamination at heterogeneous material interfaces is one of the most prominent failure modes in active implantable medical devices (AIMDs). A well-known example of an AIMD is the cochlear implant (CI). In mechanical engineering, a multitude of testing procedures are known whose data can be used for detailed modeling with respect to digital twins. Detailed, complex models for digital twins are still lacking in bioengineering since body fluid infiltration occurs both into the polymer substrate and along the metal-polymer interfaces. For a newly developed test for an AIMD or CI composed of silicone rubber and metal wiring or electrodes, a mathematical model of these mechanisms is presented. It provides a better understanding of the failure mechanisms in such devices and their validation against real-life data. The implementation utilizes COMSOL Multiphysics

Indexed as

active implantable medical devicescochlear implantCOMSOL Multiphysics®interface diffusionlifetime predictionmoving boundary diffusionvolume diffusion

Identifiers

PMID37237696
PMCPMC10215766

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.