Evidence map›Paper›PMID 37237525›Full record

ArticleBiology2023

Agouti-Signalling Protein Overexpression Reduces Aggressiveness in Zebrafish.

Ana Rocha, Alejandra Godino-Gimeno, Josep Rotllant, José Miguel Cerdá-Reverter

Open access · goldAbstract read
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Agouti-Induced Anxiety-Like Behavior Is Mediated by Central Serotonergic Pathways in Zebrafish.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ana RochaCentro Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR), Terminal de Cruzeiros do Porto de Leixões, 4450-208 Matosinhos, Portugal.ORCID 0000-0003-2165-5519
Alejandra Godino-GimenoControl of Food Intake Group, Department of Fish Physiology and Biotechnology, Instituto de Acuicultura de Torre de la Sal, IATS-CSIC, 12595 Castellon, Spain.ORCID 0000-0001-9529-0335
Josep RotllantInstituto de Investigaciones Marinas, Consejo Superior de Investigaciones Científicas (IIM-CSIC), 36208 Vigo, Spain.
José Miguel Cerdá-ReverterControl of Food Intake Group, Department of Fish Physiology and Biotechnology, Instituto de Acuicultura de Torre de la Sal, IATS-CSIC, 12595 Castellon, Spain.ORCID 0000-0003-1405-5750
Instituto de Acuicultura Torre de la Sal · ESCentro Interdisciplinar de Investigação Marinha e AmbientalConsejo Superior de Investigaciones Científicas · ES

Funding

Agencia Estatal de Investigacion BES-2017-082424Agencia Estatal de Investigacion PID2019-103969RB-C33Agencia Estatal de Investigacion PID2022-136288OB-C33European Union NextGenerationEU PRTR-C17.I1Generalitat Valenciana THINKINAZUL/2021/025
6 · The paper itself

Abstract

Feeding motivation plays a crucial role in food intake and growth. It closely depends on hunger and satiation, which are controlled by the melanocortin system. Overexpression of the inverse agonist agouti-signalling protein (ASIP) and agouti-related protein (AGRP) leads to enhanced food intake, linear growth, and weight. In zebrafish, overexpression of Agrp leads to the development of obesity, in contrast to the phenotype observed in transgenic zebrafish that overexpress

Indexed as

aggressionagouti-related protein (AGRP)ASIP1behaviourfishmelanocortinmelanocyte-stimulating hormone (MSH)proopiomelanocortin (POMC)

Identifiers

PMID37237525
PMCPMC10215356
OpenAlexW4378516740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.