Evidence map›Paper›PMID 37237452›Full record

ArticleBiology2023

Changes in Body Temperature Patterns Are Predictive of Mortality in Septic Shock: An Observational Study.

Benjamin Coiffard, Hamid Merdji, Mohamed Boucekine, Julie Helms, Raphaël Clere-Jehl, Jean-Louis Mege, Ferhat Meziani

Abstract read
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benjamin CoiffardIHU-Méditerranée Infection, IRD, AP-HM, MEPHI, Aix Marseille Université, 13005 Marseille, France.ORCID 0000-0002-8896-5346
Hamid MerdjiService de Réanimation, Nouvel Hôpital Civil, Université de Strasbourg (UNISTRA), Faculté de Médecine, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France.ORCID 0000-0002-4670-1596
Mohamed BoucekineHealth Service Research and Quality of Life Center, APHM, EA 3279 CEReSS, School of Medicine-La Timone Medical Campus, Aix Marseille Université, 13005 Marseille, France.
Julie HelmsService de Réanimation, Nouvel Hôpital Civil, Université de Strasbourg (UNISTRA), Faculté de Médecine, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France.
Raphaël Clere-JehlService de Réanimation, Nouvel Hôpital Civil, Université de Strasbourg (UNISTRA), Faculté de Médecine, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France.
Jean-Louis MegeIHU-Méditerranée Infection, IRD, AP-HM, MEPHI, Aix Marseille Université, 13005 Marseille, France.
Ferhat MezianiService de Réanimation, Nouvel Hôpital Civil, Université de Strasbourg (UNISTRA), Faculté de Médecine, Hôpitaux Universitaires de Strasbourg, 67000 Strasbourg, France.ORCID 0000-0002-1005-9095

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological rhythms are important regulators of immune functions. In intensive care unit (ICU), sepsis is known to be associated with rhythm disruption. Our objectives were to determine factors associated with rhythm disruption of the body temperature and to assess the relationship between temperature and mortality in septic shock patients; In a cohort of septic shock, we recorded body temperature over a 24-h period on day 2 after ICU admission. For each patient, the temperature rhythmicity was assessed by defining period and amplitude, and the adjusted average (mesor) of the temperature by sinusoidal regression and cosinor analysis. Analyses were performed to assess factors associated with the three temperature parameters (period, amplitude, and mesor) and mortality. 162 septic shocks were enrolled. The multivariate analysis demonstrates that the period of temperature was associated with gender (women, coefficient -2.2 h,

Indexed as

chronobiology disorderscircadian rhythmintensive care unitsmortalityseptic shocktemperature

Identifiers

PMID37237452
PMCPMC10215947

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.