Evidence map›Paper›PMID 37237420›Full record

ArticleStem cell research & therapy2023

Side population cells derived from hUCMSCs and hPMSCs could inhibit the malignant behaviors of Tn

Wen Hu, Ruisong Ding, Mengyang Wang, Panpan Huang, Xia Wei, Xingyou Hu, Tao Hu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stem cell research & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wen Hu *Department of Immunology, Binzhou Medical University, Yantai, 264003, People's Republic of China.
Ruisong Ding *Department of Immunology, Binzhou Medical University, Yantai, 264003, People's Republic of China.
Mengyang Wang *Department of Immunology, Binzhou Medical University, Yantai, 264003, People's Republic of China.
Panpan HuangDepartment of Immunology, Binzhou Medical University, Yantai, 264003, People's Republic of China.
Xia WeiDepartment of Immunology, Binzhou Medical University, Yantai, 264003, People's Republic of China.
Xingyou HuQingdao University, Qingdao, 266071, People's Republic of China. huxingyou@126.com.
Tao HuDepartment of Immunology, Binzhou Medical University, Yantai, 264003, People's Republic of China. taohu@bzmc.edu.cn.
Binzhou Medical University · CNBinzhou University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCosmc (C1GalT1C1) mutation could cause aberrant O-glycosylation and result in expression of Tn antigen on the surface of tumor cells (Tn

methodsSP cells were isolated from human umbilical cord MSCs (hUCMSCs) and human placenta MSCs (hPMSCs). Tn

resultsBoth SP cells derived from hUCMSCs and hPMSCs could inhibit proliferation and migration, promote apoptosis of CRC cells, significantly reduce Tn antigen expression on Tn

conclusionSP-hUCMSCs and SP-hPMSCs could inhibit proliferation and migration and promote apoptosis of Tn

Indexed as

Colorectal NeoplasmsSide-Population CellsAntigens, Tumor-Associated, CarbohydrateGene Expression Regulation, NeoplasticGlycosylationGlycosyltransferasesHumansAntigens, Tumor-Associated, CarbohydrateGlycosyltransferasesTn antigenColorectal cancer cellsCosmcO-glycosylationSP-hPMSCsSP-hUCMSCs

Identifiers

PMID37237420
PMCPMC10224610
OpenAlexW4378471962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.