SynthesisCritical care (London, England)2023
Variation in central venous oxygen saturation to evaluate fluid responsiveness: a systematic review and meta-analysis.
Synthesis in Critical care (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Low central venous oxygen saturation on critical care unit admission is associated with higher in-hospital mortality in critically ill patients with acute myocardial infarction.Journal of thoracic disease · 2026Article
- Use of COAnnals of intensive care · 2025Review
- Assessing fluid responsiveness with central venous oxygen saturation: the complex relationship between oxygenation and perfusion.Critical care (London, England) · 2025Article
- Variations in central venous oxygen saturation and central venous-to-arterial carbon dioxide tension difference to define fluid responsiveness: a prospective observational study.Frontiers in cardiovascular medicine · 2025Article
- Central venous oxygen saturation changes as a reliable predictor of the change of CI in septic shock: To explore potential influencing factors.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Article
- Changes in central venous-to-arterial PCOCritical care (London, England) · 2024Article
- Recent advances in cardiorespiratory monitoring in acute respiratory distress syndrome patients.Journal of intensive care · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundSince oxygen content and oxygen consumption typically remain unchanged within a short period, variation in central venous oxygen saturation (ΔScvO
methodsElectronic databases were systematically searched to identify relevant studies published before October 24, 2022. As the cutoff value of ΔScvO
resultsThis meta-analysis included 5 observational studies comprising 240 participants, of whom 133 (55%) were fluid responders. Overall, the ΔScvO
conclusionsIn mechanically ventilated patients receiving volume expansion, the ΔScvO2 during the fluid challenge is a reliable indicator of fluid responsiveness. Clinical trial registration PROSPERO, https://www.crd.york.ac.uk/prospero/ , registry number: CRD42022370192.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.