Observational studyAnnals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology2023
Longitudinal assessment of early growth in children with IgE- and non-IgE-mediated food allergy in a healthy infant cohort.
Observational study in Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Growth Deceleration in Infants With Gastrointestinal Manifestations of Cow's Milk Allergy: Case Series From Specialised Centre.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Mild Malnutrition in Children Aged 6-24 Months and Related Influencing Factors: Research From an Outpatient Clinic of Pediatric Health Care.Pediatric discovery · 2026Article
- The Impact of Maternal Dietary Avoidance During Breastfeeding on Physical Growth and Social-Emotional Development in Infants with Food Allergies: A Prospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- Diagnosis and Management of Food Protein-Induced Allergic Proctocolitis.Current gastroenterology reports · 2025Review
- Poor growth in multi-ethnic children with food allergy in Amsterdam.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Article
- Rates of parent-reported allergic conditions in children at-risk of celiac disease.JPGN reports · 2025Article
- Risk of IgE-mediated food allergy and its impact on child growth: A machine learning approach.The World Allergy Organization journal · 2025Article
- Evaluation of Intestinal Permeability Using Serum Biomarkers in Learning Early About Peanut Allergy Trial.Allergy · 2025Article
- Prevalence of Cow's Milk Allergy in Infants from an Urban, Low-Income Population in Chile: A Cohort Study.Nutrients · 2025Article
- Tolerance of Infants Fed a Hydrolyzed Rice Infant Formula with 2'-Fucosyllactose (2'-FL) Human Milk Oligosaccharide (HMO).Nutrients · 2024Article
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundThere are conflicting associations reported between food allergies (FAs) and poor growth, with some indication that children with multiple FAs are at highest risk.
objectiveWe analyzed longitudinal weight-for-length (WFL) trajectories from our healthy cohort to evaluate growth in children with IgE-mediated FAs and food protein-induced allergic proctocolitis (FPIAP), a non-IgE-mediated FA.
methodsOur observational cohort of 903 healthy newborn infants was prospectively enrolled to evaluate the development of FAs. Longitudinal mixed effects modeling was used to compare differences in WFL among children with IgE-FA and FPIAP, compared with unaffected children, through age 2.
resultsAmong the 804 participants who met inclusion criteria, FPIAP cases had significantly lower WFL than unaffected controls during active disease, which resolved by 1 year of age. In contrast, children with IgE-FA had significantly lower WFL than unaffected controls after 1 year. We also found that children with IgE-FA to cow's milk had significantly lower WFL over the first 2 years of age. Children with multiple IgE-FAs had markedly lower WFL over the first 2 years of age.
conclusionChildren with FPIAP have impaired growth during active disease in the first year of age which resolves, whereas children with IgE-FA, particularly those with multiple IgE-FA, have impaired growth more prominently after the first year of age. It may be appropriate to focus nutritional assessment and interventions accordingly during these higher risk periods in these patient populations.
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