Evidence map›Paper›PMID 37236422›Full record

ArticleKidney international2023

A novel role for the histone modifier PRDM6 and an opportunity to understand hypertension.

Jason P Smith, Maria Luisa S Sequeira-Lopez, R Ariel Gomez

Abstract readComment
In one paragraph

Article in Kidney international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jason P SmithDepartment of Pediatrics, Child Health Research Center, University of Virginia, Charlottesville, Virginia, USA.
Maria Luisa S Sequeira-LopezDepartment of Pediatrics, Child Health Research Center, University of Virginia, Charlottesville, Virginia, USA. Electronic address: MSL7U@uvahealth.org.
R Ariel GomezDepartment of Pediatrics, Child Health Research Center, University of Virginia, Charlottesville, Virginia, USA. Electronic address: rg@uvahealth.org.

Funding

Single-Cell Epigenomics, Transcriptomics, and Bioinformatics CoreP50DK096373 · NIDDK · UNIVERSITY OF VIRGINIA · PI PATRICIO E. RAY · 2012 to 2026
$13.8M
Plasticity of renin cells in the kidney vasculatureR01DK116718 · NIDDK · UNIVERSITY OF VIRGINIA · PI GOMEZ, ROBERTO ARIEL · 2018 to 2022
$2.8M
Renin cell identity and blood pressure homeostasisR01HL148044 · NHLBI · UNIVERSITY OF VIRGINIA · PI SEQUEIRA-LOPEZ, MARIA LUISA SOLEDAD · 2020 to 2023
$2.7M
Fate of the kidney vasculature during partial neonatal ureteral obstructionR01DK116196 · NIDDK · UNIVERSITY OF VIRGINIA · PI SEQUEIRA-LOPEZ, MARIA LUISA SOLEDAD · 2018 to 2021
$1.5M
NHLBI NIH HHS R01 HL148044NIDDK NIH HHS P50 DK096373NIDDK NIH HHS R01 DK116196NIDDK NIH HHS R01 DK116718
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HistonesHypertensionAngiotensin IIHumansMuscle, Smooth, VascularReninRenin-Angiotensin SystemAngiotensin IIHistonesReninchromatin regulationhomeostasisjuxtaglomerular cellrenin-angiotensin systemrenin cellvascular smooth muscle cell

Identifiers

PMID37236422
PMCPMC10529860

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.