Evidence map›Paper›PMID 37236191›Full record

ArticleCell host & microbe2023

Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox.

Sarah Adamo, Yu Gao, Takuya Sekine, Akhirunnesa Mily, Jinghua Wu, Elisabet Storgärd, Victor Westergren, Finn Filén, Carl-Johan Treutiger, Johan K Sandberg and 9 more

Abstract read
In one paragraph

Article in Cell host & microbe, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Waning humoral immunity following monkeypox virus infection and vaccination, Canada, 2020 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
    Observational
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Sarah AdamoDepartment of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Stockholm 14152, Sweden.
Yu GaoDepartment of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Stockholm 14152, Sweden.
Takuya SekineDepartment of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Stockholm 14152, Sweden.
Akhirunnesa MilyDepartment of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Stockholm 14152, Sweden.
Jinghua WuDepartment of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Stockholm 14152, Sweden.
Elisabet StorgärdDepartment of Infectious Diseases/Venhälsan, Södersjukhuset, Stockholm 11861, Sweden.
Victor WestergrenDepartment of Infectious Diseases/Venhälsan, Södersjukhuset, Stockholm 11861, Sweden.
Finn FilénDepartment of Infectious Diseases/Venhälsan, Södersjukhuset, Stockholm 11861, Sweden.
Carl-Johan TreutigerDepartment of Infectious Diseases/Venhälsan, Södersjukhuset, Stockholm 11861, Sweden.
Johan K SandbergDepartment of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Stockholm 14152, Sweden.
Matti SällbergDepartment of Laboratory Medicine, Division of Clinical Immunology, Karolinska Institutet, Stockholm 14152, Sweden.
Peter BergmanDepartment of Laboratory Medicine, Division of Clinical Immunology, Karolinska Institutet, Stockholm 14152, Sweden; Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm 14152, Sweden.
Sian Llewellyn-LaceyDivision of Infection and Immunity, Cardiff University School of Medicine, University Hospital of Wales, Cardiff CF14 4ER, UK.
Hans-Gustaf LjunggrenDepartment of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Stockholm 14152, Sweden.
David A PriceDivision of Infection and Immunity, Cardiff University School of Medicine, University Hospital of Wales, Cardiff CF14 4ER, UK; Systems Immunity Research Institute, Cardiff University School of Medicine, University Hospital of Wales, Cardiff CF14 4ER, UK.
Anna-Mia EkströmDepartment of Infectious Diseases/Venhälsan, Södersjukhuset, Stockholm 11861, Sweden; Department of Global Public Health, Karolinska Institutet, Stockholm 17176, Sweden.
Alessandro SetteCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA, USA; Department of Pathology, University of California, San Diego, La Jolla, CA 92093, USA.
Alba GrifoniCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA, USA.
Marcus BuggertDepartment of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Stockholm 14152, Sweden. Electronic address: marcus.buggert@ki.se.

Funding

Large Scale T Cell Epitope Discovery:Global identification of epitopes derived from Zika (ZIKV), Chikungunya (CHIKV) viruses following natural infection and vaccination75N93019C00065 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI MITCHELL, MAYA · 2019 to 2023
$7.3M
NIAID NIH HHS 75N93019C00065
6 · The paper itself

Abstract

Mpox represents a persistent health concern with varying disease severity. Reinfections with mpox virus (MPXV) are rare, possibly indicating effective memory responses to MPXV or related poxviruses, notably vaccinia virus (VACV) from smallpox vaccination. We assessed cross-reactive and virus-specific CD4

Indexed as

Mpox, MonkeypoxPoxviridaeSmallpoxCD8-Positive T-LymphocytesHumansVaccinia virusinfectious diseaseslong-lived memory T cellsmonkeypoxmpoxMPXVT cellsvaccinia virusVACVviral immunity

Identifiers

PMID37236191
PMCPMC10211501

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.