ArticleImmunity2023
Allogeneic immunity clears latent virus following allogeneic stem cell transplantation in SIV-infected ART-suppressed macaques.
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Article in Immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
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Who cites it
21 citing papers in PubMed, 22 citations in OpenAlex.
- Combination therapy with broadly neutralizing antibodies, antiretroviral therapy and CCR5 blockade limits viral reservoir seeding in infant macaque model of HIV.Nature microbiology · 2026Article
- CD8ɑ+ cells suppress SIV replication without the development of mutations within MHC class-I-restricted epitopes during post-treatment control.Journal of virology · 2026Article
- Long-term HIV-1 remission achieved through allogeneic haematopoietic stem cell transplant from a CCR5Δ32/Δ32 sibling donor.Nature microbiology · 2026Article
- Article
- The power of ten in HIV remission: insights from hematopoietic stem cell transplantation.Current opinion in HIV and AIDS · 2025Review
- Applications and limitations of the passenger hypothesis for HIV reservoir persistence and cure.Journal of virology · 2025Review
- Deep Thought on the HIV Cured Cases: Where Have We Been and What Lies Ahead?Biomolecules · 2025Review
- HIV-1 remission following stem cell transplant without CCR5Δ32 mutation.Nature medicine · 2024Article
- Sustained HIV remission after allogeneic hematopoietic stem cell transplantation with wild-type CCR5 donor cells.Nature medicine · 2024Article
- A model of lymphocryptovirus-associated post-transplant lymphoproliferative disorder in immunosuppressed Mauritian cynomolgus macaques.PLoS pathogens · 2024Article
- Effect of metabolic status on response to SIV infection and antiretroviral therapy in nonhuman primates.JCI insight · 2024Article
- Cytomegalovirus vaccine vector-induced effector memory CD4 + T cells protect cynomolgus macaques from lethal aerosolized heterologous avian influenza challenge.Nature communications · 2024Article
- Repair Effect of Umbilical Cord Mesenchymal Stem Cells Embedded in Hydrogel on Mouse Insulinoma 6 Cells Injured by Streptozotocin.Polymers · 2024Article
- Immune restoration by TIGIT blockade is insufficient to control chronic SIV infection.Journal of virology · 2024Article
- Dynamics of virological and immunological markers of HIV persistence after allogeneic haematopoietic stem-cell transplantation in the IciStem cohort: a prospective observational cohort study.The lancet. HIV · 2024Observational
- HIV Reservoirs and Treatment Strategies toward Curing HIV Infection.International journal of molecular sciences · 2024Review
- Antiretrovirals to CCR5 CRISPR/Cas9 gene editing - A paradigm shift chasing an HIV cure.Clinical immunology (Orlando, Fla.) · 2023Review
- CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection.PLoS pathogens · 2023Article
- Progress Note 2024: Curing HIV; Not in My Lifetime or Just Around the Corner?Pathogens & immunity · 2023Article
- Identification of Vancomycin Resistance in Methicillin-resistantFrontiers in immunology · 2023Article
Corrections and comments
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Authors and funding
43 authors at 4 institutions in 1 country.
Helen L WuVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA.
Kathleen Busman-SahayVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA.
Whitney C WeberVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA.
Courtney M WaytashekVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA.
Carla D BoyleVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA.
Katherine B BatemanVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA.
Jason S ReedVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA.
Joseph M HwangVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA.
Christine Shriver-MunschOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Tonya SwansonOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Mina NorthrupVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Kimberly ArmantroutOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Heidi PriceOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Mitch Robertson-LeVayOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Samantha UttkeOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Mithra R KumarDepartment of Medicine and Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA.
Emily J FrayDepartment of Medicine and Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA.
Sol Taylor-BrillVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA.
Stephen BondocVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA.
Rebecca AgnorBiostatistics Shared Resource, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Stephanie L JunellDivision of Medical Physics, Department of Radiation Medicine, Oregon Health & Science University, Portland, OR 97239, USA.
Alfred W LegasseOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Cassandra MoatsOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Rachele M BochartOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Joseph SciurbaOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Benjamin N BimberOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Michelle N SullivanOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Brandy DozierOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Rhonda P MacAllisterOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Theodore R HobbsOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Lauren D MartinOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Angela Panoskaltsis-MortariDivision of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, 55454, USA.
Lois M A ColginOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Robert F SilicianoDepartment of Medicine and Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA.
Janet D SilicianoDepartment of Medicine and Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA.
Jacob D EstesVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Jeremy V SmedleyOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Michael K AxthelmOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Gabrielle MeyersDivision of Blood and Marrow Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Richard T MaziarzDivision of Blood and Marrow Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Benjamin J BurwitzVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Jeffrey J StantonOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA.
Jonah B SachaVaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR 97007, USA; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR 97007, USA. Electronic address: sacha@ohsu.edu.
Oregon National Primate Research Center · USOregon Health & Science University · USHoward Hughes Medical Institute · USUniversity of Minnesota · US
Funding
Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9MA nonhuman primate model of stem cell transplantation to understand determinants of post-transplant SIV clearanceR01AI129703 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI SACHA, JONAH B. · 2017 to 2025
$7.8MProgram in Biomedical SciencesT32GM142619 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Jeffrey Wallace Tyner · 2021 to 2026
$3.2MNon-canonical epitope presentation and antigen processing by MHC-ER01AI175459 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI Klaus J Fruh, Jonah B. Sacha · 2023 to 2026
$2.8MGraft versus host immunity in SIV clearance following stem cell transplantation.R21AI112433 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI SACHA, JONAH B. · 2014 to 2015
$481kNIAID NIH HHS R01 AI129703NIAID NIH HHS R01 AI175459NIAID NIH HHS R21 AI112433NIGMS NIH HHS T32 GM142619NIH HHS P51 OD011092
Abstract
Allogeneic hematopoietic stem cell transplantation (alloHSCT) from donors lacking C-C chemokine receptor 5 (CCR5
Indexed as
Hematopoietic Stem Cell TransplantationHIV InfectionsSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAnimalsMacaca fascicularisViral LoadCCR5GVHDHIVHSCTSIV
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