Evidence map›Paper›PMID 37235572›Full record

ArticlePloS one2023

Prevalence of psychological distress, quality of life, and satisfaction among patients and family members following comprehensive genomic profiling testing: Protocol of the Quality of life for Cancer genomics and Advanced Therapeutics (Q-CAT) study.

Makoto Nishino, Maiko Fujimori, Takafumi Koyama, Makoto Hirata, Noriko Tanabe, Toshio Shimizu, Noboru Yamamoto, Yosuke Uchitomi

Abstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Makoto NishinoDepartment of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan.
Maiko FujimoriDivision of Supportive Care, Survivorship and Translational Research, National Cancer Center Institute for Cancer Control, Tokyo, Japan.ORCID 0000-0003-1639-3390
Takafumi KoyamaDepartment of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan.
Makoto HirataDepartment of Genetic Medicine and Services, National Cancer Center Hospital, Tokyo, Japan.
Noriko TanabeDepartment of Genetic Medicine and Services, National Cancer Center Hospital, Tokyo, Japan.
Toshio ShimizuDepartment of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan.
Noboru YamamotoDepartment of Experimental Therapeutics, National Cancer Center Hospital, Tokyo, Japan.
Yosuke UchitomiInnovation Center for Supportive, Palliative and Psychosocial Care and Department of Psycho-Oncology, National Cancer Center Hospital, and Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision medicine is rapidly changing the diagnostic and treatment spectrum of oncology. In May 2019, comprehensive genomic profiling (CGP) (somatic and/or germline) was approved for reimbursement in Japan. While the promise of novel and targeted therapies has elevated hopes for the benefits of CGP, the lack of relevant genomic findings and/or limited access to relevant therapies remain important themes in this field. These challenges may also negatively influence the psychology of both cancer patients and their family members. However, few studies have reported longitudinal data on quality of life (QOL) with CGP. Here, we report the protocol of a prospective study, Q-CAT (QOL for Cancer genomics and Advanced Therapeutics among patients and their family members), which aims to explore the mental burden on patients and families arising from the implementation of CGP testing by collecting real-world longitudinal data using outcomes obtained with an electronic patient report, known as ePRO. This study has been registered with the Japan Registry of Clinical Trials (jRCT1030200039).

Indexed as

NeoplasmsPsychological DistressGenomicsHumansPatient SatisfactionPersonal SatisfactionPrevalenceProspective StudiesQuality of Life

Identifiers

PMID37235572
PMCPMC10218744

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.