Evidence map›Paper›PMID 37235393›Full record

ArticleVeterinary sciences2023

Repeated Administration of the Cannabinoid WIN Alters the Isoflurane-Sparing Effect of Morphine and Dexmedetomidine.

José Antonio Ibancovichi, Julio Raúl Chávez-Monteagudo, Pedro Sánchez-Aparicio, Marco Antonio De Paz-Campos

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

José Antonio IbancovichiDepartamento de Anestesiología y Analgesia, Facultad de Medicina Veterinaria, Universidad Autónoma del Estado de México, UAEM, Toluca 50000, Mexico.
Julio Raúl Chávez-MonteagudoDepartamento de Ciencias Pecuarias, Facultad de Estudios Superiores Cuautitlán, Hospital de Pequeñas Especies, Universidad Nacional Autónoma de México, UNAM, Cuautitlán Izcalli 54740, Mexico.
Pedro Sánchez-AparicioDepartamento de Farmacología, Facultad de Medicina Veterinaria, Universidad Autónoma del Estado de México, UAEM, Toluca 50000, Mexico.ORCID 0000-0002-6511-6595
Marco Antonio De Paz-CamposDepartamento de Ciencias Biológicas, Facultad de Estudios Superiores Cuautitlán, Hospital de Pequeñas Especies, Universidad Nacional Autónoma de México, UNAM, Cuautitlán Izcalli 54740, Mexico.
Universidad Autónoma del Estado de México · MXUniversidad de Cuautitlán Izcalli · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impacts of morphine and dexmedetomidine on the MAC of isoflurane were studied in rats constantly medicated with the cannabinoid WIN 55,212-2.

methodsPrior to the administration of morphine, the MAC was measured in both untreated rats (MAC

resultsMAC

conclusionsMedication with a cannabinoid for 21 days augmented the MAC of isoflurane. The sparing effect of morphine on isoflurane is lower in rats constantly medicated with a cannabinoid. The sparing effect of dexmedetomidine on the minimum alveolar concentration of isoflurane is greater in rats repeatedly medicated with a cannabinoid.

Indexed as

cannabinoid WIN 55,212-2dexmedetomidineminimum alveolar concentration of isofluranemorphinerats

Identifiers

PMID37235393
PMCPMC10222237
OpenAlexW4366826852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.