Evidence map›Paper›PMID 37234925›Full record

ArticleJournal of the ASEAN Federation of Endocrine Societies2023

The Effect of Glucocorticoids on

Sam Ezrael Dela Cruz, Pia Bagamasbad

Open access · diamondAbstract read
In one paragraph

Article in Journal of the ASEAN Federation of Endocrine Societies, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sam Ezrael Dela CruzNational Institute of Molecular Biology and Biotechnology, University of the Philippines Diliman.
Pia BagamasbadNational Institute of Molecular Biology and Biotechnology, University of the Philippines Diliman.
University of the Philippines Diliman · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: X-linked Dystonia Parkinsonism (XDP) is associated with a SINE-VNTR- Alu (SVA) retrotransposon insertion in an intron of the Methodology: We performed Results: A transcription factor binding site search revealed three binding sites for GR within the XDP-SVA-two within the SINE region and one in the Alu region. Promoter-reporter assays showed induction of XDP-SVA promoter activity upon CORT treatment that was dependent on the cell line and XDP-SVA hexamer repeat length. Gene expression analysis showed that baseline Conclusion: Using reporter assays, the XDP-SVA was shown to exhibit CORT-dependent transcriptional activation. Gene expression analysis also showed that GC signaling may influence

Indexed as

DystoniaParkinsonian DisordersDystonic DisordersGenetic Diseases, X-LinkedGlucocorticoidsHEK293 CellsHumansMifepristoneTranscription Factor TFIIDTranscription, GeneticGlucocorticoidsMifepristoneTranscription Factor TFIIDglucocorticoidsneurodegenerative diseasestressTAF1XDP

Identifiers

PMID37234925
PMCPMC10207867
OpenAlexW4312932269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.