Evidence map›Paper›PMID 37234822›Full record

ArticleHemaSphere2023

Unmet Clinical Needs in the Management of Idiopathic Multicentric Castleman Disease: A Consensus-based Position Paper From an ad hoc Expert Panel.

Pier Luigi Zinzani, Marco Paulli, Luca Arcaini, Emanuel Della Torre, Simone Ferrero, Amalia Figuera, Ferdinando Frigeri, Maurizio Martelli, Elena Sabattini, Riccardo Scarpa and 1 more

Open access · goldAbstract read
In one paragraph

Article in HemaSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Pier Luigi ZinzaniIRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia "Seràgnoli," Bologna, Italy.
Marco PaulliUnit of Anatomic Pathology, Department of Molecular Medicine, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Luca ArcainiDepartment of Molecular Medicine, University of Pavia, Italy.
Emanuel Della TorreUniversità Vita-Salute San Raffaele, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Simone FerreroDepartment of Molecular Biotechnologies and Health Sciences, Hematology Division, University of Torino, Italy.
Amalia FigueraDivision of Hematology, AOU Policlinico "G. Rodolico-S. Marco," Catania, Italy.
Ferdinando FrigeriUOC Ematologia a Indirizzo Oncologico, AORN "Sant'Anna e San Sebastiano," Caserta, Italy.
Maurizio MartelliHematology Unit, Department of Translational and Precision Medicine, "Sapienza" University, Rome, Italy.
Elena SabattiniHemathopathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policinico di S. Orsola, Bologna, Italy.
Riccardo ScarpaDepartment of Medicine-DIMED, University of Padova, Padua, Italy.
Giovanni BarosiCenter for the Study of Myelofibrosis, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITCa' Foncello Hospital · ITIstituto di Ematologia di Bologna · ITIstituto di Ricovero e Cura a Carattere Scientifico San RaffaeleOspedale Sant'Anna · ITPoliclinico San Matteo Fondazione · ITPoliclinico Universitario di Catania · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Castleman disease describes a group of heterogeneous clinicopathological disorders now included in the tumor-like lesions with B-cell predominance of the World Health Organization classification. Managing idiopathic multicentric Castleman disease (iMCD) is challenging, because few systematic studies or comparative randomized clinical trials have been conducted. International, consensus evidence-based guidelines for iMCD were published in 2018, but gaps in the therapeutic options for difficult-to-treat patients, who do not respond to siltuximab and other conventional therapies, still exist. This article presents the results of group discussion among an

Identifiers

PMID37234822
PMCPMC10208718
OpenAlexW4378086284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.