Evidence map›Paper›PMID 37234700›Full record

ArticleGynecologic oncology reports2023

The clinico pathological features and survival in serous endometrial cancers.

Amrita Datta, Vinotha Thomas, Ajit Sebastian, Rachel George, Anitha Thomas, Thomas Samuel Ram, Sherin Daniel, K Reka, Abraham Peedicayil

Abstract read
In one paragraph

Article in Gynecologic oncology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amrita DattaDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Vinotha ThomasDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Ajit SebastianDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Rachel GeorgeDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Anitha ThomasDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Thomas Samuel RamDepartment of Radiation Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Sherin DanielDepartment of Pathology, Christian Medical College, Vellore, Tamil Nadu, India.
K RekaDepartment of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.
Abraham PeedicayilDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background & Introduction: Serous cancers are a biologically aggressive variety of endometrial cancer (EC) with a high rate of recurrence and mortality among all the subtypes. Herein we describe our experience with serous endometrial cancer. Objective: This study was conducted to identify the clinicopathological characteristics, treatment modalities and survival outcomes in women diagnosed with serous endometrial malignancies. Methods: This was a retrospective descriptive analysis of data on patients diagnosed with serous endometrial tumours between January 2010 to September 2019 in our institute collected from electronic medical records. Descriptive statistics such as proportions, means and standard deviations and Cox regression hazards model on risk factors were performed. Survival was plotted by Kaplan-Meier curves. Results: During the study period, 32 (5.7%) patients out of 564 diagnosed cases of endometrial cancer had serous histology. The mean age at diagnosis was 62.5 years (SD 7.6) while mean BMI was 26.4 kg/m Conclusion: Serous endometrial cancers are an intrusive subtype of EC. Comprehensive surgical staging with optimal cytoreduction should be aimed at. Adequate upfront molecular categorization of these tumors is mandated. Adjuvant therapy with chemotherapy and radiation is given in postoperative setting. Targeted therapies and immunotherapy could be considered in recurrences.

Indexed as

HistologyOverall survivalRecurrence free survivalSerous endometrial cancerTreatment

Identifiers

PMID37234700
PMCPMC10206430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.