ArticleFrontiers in microbiology2023
Causal effects of gut microbiota on sepsis: a two-sample Mendelian randomization study.
Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Causal effects of basal metabolic rate and adiposity on obstructive sleep apnea: univariable, multivariable, and bidirectional Mendelian randomization evidence.Future science OA · 2026Article
- Article
- Identifying the causal relationship between gut microbiota and lymphoma disease: a Mendelian randomization study and meta-analysis.Archives of medical science : AMS · 2026Article
- Dietary, metabolic and gut microbiota influences on primary ovarian failure: a two-sample Mendelian randomization study.Asia Pacific journal of clinical nutrition · 2025Article
- Immune Cells Mediate the Causal Pathway Linking Multisite Chronic Pain to Asthma: A Mediation Mendelian Randomization Study.Journal of pain research · 2025Article
- Genetically instrumented circulating metabolites and hepatobiliary cancer risk: A multi-tiered Mendelian randomization and functional interrogation.Frontiers in oncology · 2025Article
- Gut microbiota and sepsis-associated encephalopathy: pathogenesis and precision therapies.Frontiers in neuroscience · 2025Review
- Exploring the relationship between creatine supplementation and renal function: insights from Mendelian randomization analysis.Renal failure · 2024Article
- Causal association of circulating inflammatory proteins on neurodegenerative diseases: Insights from a mendelian randomization study.Journal of cellular and molecular medicine · 2024Article
- LeechWorld journal of gastroenterology · 2024Article
- Genetic causal association between gut microbiota and sepsis: Evidence from a two-sample bidirectional Mendelian randomization analysis.Journal of intensive medicine · 2024Article
- Blood metabolomic and postpartum depression: a mendelian randomization study.BMC pregnancy and childbirth · 2024Article
- Influence of Varied Environment Conditions on the Gut Microbiota of Yaks.Animals : an open access journal from MDPI · 2024Article
- Causal relationship between telomere length and sepsis: a bidirectional Mendelian randomization study.Scientific reports · 2024Article
- Supplementing Ryegrass Ameliorates Commercial Diet-Induced Gut Microbial Dysbiosis-Associated Spleen Dysfunctions by Gut-Microbiota-Spleen Axis.Nutrients · 2024Article
- Genetic insights into the gut microbiota, herpes zoster, and postherpetic neuralgia: a bidirectional two-sample Mendelian randomization study.Frontiers in genetics · 2024Article
- The plasma lipids with different fatty acid chains are associated with the risk of hemorrhagic stroke: a Mendelian randomization study.Frontiers in neurology · 2024Article
- Causal relationships of gut microbiota, plasma metabolites, and metabolite ratios with diffuse large B-cell lymphoma: a Mendelian randomization study.Frontiers in microbiology · 2024Article
- Behavior, hormone, and gut microbiota change by YYNS intervention in an OVX mouse model.Frontiers in cellular and infection microbiology · 2024Article
- Gut microbiota and sepsis and sepsis-related death: a Mendelian randomization investigation.Frontiers in immunology · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Recent studies had provided evidence that the gut microbiota is associated with sepsis. However, the potential causal relationship remained unclear. Methods: The present study aimed to explore the causal effects between gut microbiota and sepsis by performing Mendelian randomization (MR) analysis utilizing publicly accessible genome-wide association study (GWAS) summary-level data. Gut microbiota GWAS ( Results: Our study suggested that increased abundance of Conclusion: This study firstly found suggestive evidence of beneficial or detrimental causal associations of gut microbiota on sepsis risk by applying MR approach, which may provide valuable insights into the pathogenesis of microbiota-mediated sepsis and strategies for sepsis prevention and treatment.
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