ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2023
Isolation and identification of novel selective antitumor constituents, sidrin and sidroside, from
Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors at 3 institutions in 3 countries.
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Abstract
Background: The leaves of Objectives: We aimed to investigate and isolate cytotoxic compounds with selective antitumor effects from the leaves of Methods: Powdered, dried leaves were subjected to methanol extraction and fractionated using Results: The chloroform and aqueous methanol fractions of the leaves showed cytotoxic activity. Two compounds were successfully isolated and named "sidrin" (13-β-hydroxy-lup-20(30)-ene-2,3-β-epoxy-28-carboxylate) and "sidroside" (3- Conclusions: These results suggest tumor-selective cytotoxicity of sidrin and sidroside.
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