Evidence map›Paper›PMID 37234329›Full record

ReviewJournal of oral and maxillofacial pathology : JOMFP

Liquid biopsy and its significance in tumour - Detection in the field of pathology.

Upma Tomar, Neeraj Grover, Sanjeev Tomar, Kanika Bhalla, Shreya Singh

Open access · greenAbstract readReview
In one paragraph

Review in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. [Progression and application of circulating tumor DNA in lymphoma].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2024
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Upma TomarDepartment of Oral and Maxillofacial Pathology and Microbiology, Inderprastha Dental College and Hospital, Ghaziabad, NCR Delhi, India.
Neeraj GroverDepartment of Oral and Maxillofacial Pathology and Microbiology, Santosh Dental College and Hospital, Santosh Deemed to be University, Ghaziabad, NCR Delhi, India.
Sanjeev TomarDepartment of Oral and Maxillofacial Surgery, Santosh Dental College and Hospital, Santosh Deemed to be University, Ghaziabad, NCR Delhi, India.
Kanika BhallaDepartment of Oral and Maxillofacial Pathology and Microbiology, Santosh Dental College and Hospital, Santosh Deemed to be University, Ghaziabad, NCR Delhi, India.
Shreya SinghDepartment of Oral and Maxillofacial Pathology and Microbiology, Santosh Dental College and Hospital, Santosh Deemed to be University, Ghaziabad, NCR Delhi, India.
Santosh University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of cancer has remarkably improved because of increased knowledge of the abnormalities at the molecular level, which results in human cancer growth. This has initiated the development of ever more successful as well as effective targeted cancer therapies. Detection of cancer is diagnosed basically by performing routine biopsy/cytology, which has many drawbacks. Therefore, the concept of liquid biopsy has been introduced to oncology, which has the potential to revolutionise the management of cancer patients, eliminating the invasive procedures needed to obtain tissue samples and provide information. Liquid biopsy is the analysis of tumour cells or tumour cell products obtained from blood or other body fluids, providing a broad range of opportunities in the field of pathology. Here, we focus on the most prominent liquid biopsy markers, circulating tumour cells and circulating tumour-derived deoxyribonucleic acid (DNA), in the blood of patients. In this review, we discuss recent clinical studies on these biomarkers for early detection and prognostication of cancer, which helps in successful management. Hence, liquid biopsy is introduced with great promise for personalised medicine because of its ability to provide multiple non-invasive snapshots of the primary and metastatic tumours.

Indexed as

Cancercell-free DNAcell-free RNAcirculating tumour cellsliquid biopsy

Identifiers

PMID37234329
PMCPMC10207190
OpenAlexW4367154547

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.