ArticleFrontiers in psychiatry2023
The time scales of irreversibility in spontaneous brain activity are altered in obsessive compulsive disorder.
Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Magnetoencephalography in human neuroscience research: planning, piloting, implementation and quality assurance.Nature protocols · 2026Review
- Multiscale Permutation Time Irreversibility Analysis of MEG in Patients with Schizophrenia.Entropy (Basel, Switzerland) · 2025Article
- Differential motor neuron activity in rats during successful and failed grasping.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Algorithmic Approaches for Assessing Multiscale Irreversibility in Time Series: Review and Comparison.Entropy (Basel, Switzerland) · 2025Review
- Revisiting the Characterization of Resting Brain Dynamics with the Permutation Jensen-Shannon Distance.Entropy (Basel, Switzerland) · 2024Article
- A synergetic turn in cognitive neuroscience of brain diseases.Trends in cognitive sciences · 2024Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We study how obsessive-compulsive disorder (OCD) affects the complexity and time-reversal symmetry-breaking (irreversibility) of the brain resting-state activity as measured by magnetoencephalography (MEG). Comparing MEG recordings from OCD patients and age/sex matched control subjects, we find that irreversibility is more concentrated at faster time scales and more uniformly distributed across different channels of the same hemisphere in OCD patients than in control subjects. Furthermore, the interhemispheric asymmetry between homologous areas of OCD patients and controls is also markedly different. Some of these differences were reduced by 1-year of Kundalini Yoga meditation treatment. Taken together, these results suggest that OCD alters the dynamic attractor of the brain's resting state and hint at a possible novel neurophysiological characterization of this psychiatric disorder and how this therapy can possibly modulate brain function.
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