Evidence map›Paper›PMID 37233982›Full record

ArticleACS applied materials & interfaces2023

Layer-by-Layer Deposition of Low-Solid Nanochitin Emulgels Creates Porous Structures for High Cell Attachment and Proliferation.

Ya Zhu, Esko Kankuri, Xue Zhang, Zhangmin Wan, Xin Wang, Siqi Huan, Long Bai, Shouxin Liu, Orlando J Rojas

Open access · hybridAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Ya ZhuBiobased Colloids and Materials Group, Department of Bioproducts and Biosystems, Aalto University, Vuorimiehentie 1, P.O. Box 16300, 02150 Espoo, Finland.ORCID 0000-0003-2885-7105
Esko KankuriDepartment of Pharmacology, Faculty of Medicine, University of Helsinki, Viikinkaari 5E, P.O. Box 56, 00014 Helsinki, Finland.ORCID 0000-0002-2193-8773
Xue ZhangBiobased Colloids and Materials Group, Department of Bioproducts and Biosystems, Aalto University, Vuorimiehentie 1, P.O. Box 16300, 02150 Espoo, Finland.
Zhangmin WanBioproducts Institute, Department of Chemical & Biological Engineering, Department of Chemistry, and Department of Wood Science, The University of British Columbia, 2360 East Mall, Vancouver, British Columbia V6T 1Z3, Canada.
Xin WangKey Laboratory of Biobased Material Science and Technology (Ministry of Education), Northeast Forestry University, Harbin 150040, Heilongjiang, P. R. China.
Siqi HuanKey Laboratory of Biobased Material Science and Technology (Ministry of Education), Northeast Forestry University, Harbin 150040, Heilongjiang, P. R. China.ORCID 0000-0003-1688-9484
Long BaiBioproducts Institute, Department of Chemical & Biological Engineering, Department of Chemistry, and Department of Wood Science, The University of British Columbia, 2360 East Mall, Vancouver, British Columbia V6T 1Z3, Canada.ORCID 0000-0003-3356-9095
Shouxin LiuKey Laboratory of Biobased Material Science and Technology (Ministry of Education), Northeast Forestry University, Harbin 150040, Heilongjiang, P. R. China.ORCID 0000-0002-0491-8885
Orlando J RojasBiobased Colloids and Materials Group, Department of Bioproducts and Biosystems, Aalto University, Vuorimiehentie 1, P.O. Box 16300, 02150 Espoo, Finland.ORCID 0000-0003-4036-4020
Northeast Forestry University · CNAalto University · FIUniversity of British Columbia · CAUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Direct ink writing (DIW) is a customizable platform to engineer complex constructs from biobased colloids. However, the latter usually display strong interactions with water and lack interparticle connectivity, limiting one-step processing into hierarchically porous structures. We overcome such challenges by using low-solid emulgel inks stabilized by chitin nanofibrils (nanochitin, NCh). By using complementary characterization platforms, we reveal NCh structuring into spatially controlled three-dimensional (3D) materials that generate multiscale porosities defined by emulsion droplet size, ice templating, and DIW infill density. The extrusion variables, key in the development of surface and mechanical features of printed architectures, are comprehensively analyzed by using molecular dynamics and other simulation approaches. The obtained scaffolds are shown for their hierarchical porous structures, high areal density, and surface stiffness, which lead to excellent modulation of cell adhesion, proliferation, and differentiation, as tested with mouse dermal fibroblast expressing green fluorescent proteins.

Indexed as

Printing, Three-DimensionalTissue ScaffoldsAnimalsCell AdhesionCell ProliferationEmulsionsMicePorosityEmulsions3D printingcell proliferationhierarchical porositynanochitinPickering emulsion

Identifiers

PMID37233982
PMCPMC10251351
OpenAlexW4378348841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.