ArticleAging clinical and experimental research2023
Survival following vertebral compression fractures in population over 65 years old.
Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Mortality After Osteoporotic Vertebral Body Fractures: Cement Augmentation Versus Conservative Treatment—A Systematic Review and Meta-Analysis.Deutsches Arzteblatt international · 2025Pooled it
- One-year mortality and functional outcome of inpatients aged 85 and older with thoracolumbar vertebral fractures: differences between operative and conservative treatment.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Review
- The Journey of Acromegaly Towards Treatment: A Single-Center Study.Journal of personalized medicine · 2026Article
- Predicting long-term clinical mortality of elderly patients with vertebral compression fractures.Frontiers in medicine · 2026Article
- Impact of body composition on fragility fractures in US elderly adults: a population-based study.BMC geriatrics · 2025Article
- Impact of Mediterranean diet on mortality in vertebral compression fracture patients.Arthritis research & therapy · 2025Article
- Review
- The effectiveness of balloon kyphoplasty compared to conservative treatment for osteoporotic vertebral compression fractures: A systematic review and meta-analysis.Interventional pain medicine · 2025Review
- Low-energy vertebral fractures requiring a fusion in the elderly associate higher mortality than high-energy injuries.Brain & spine · 2025Article
- The global burden of vertebral fractures caused by falls among individuals aged 55 and older, 1990 to 2021.PloS one · 2025Article
- Impact of dementia and mild cognitive impairment on bone health in older people.Aging clinical and experimental research · 2024Review
- Recommendations for the optimal use of bone forming agents in osteoporosis.Aging clinical and experimental research · 2024Review
- Article
- The statistical fragility of vertebroplasty outcomes: A systematic review of randomized controlled trials.Journal of craniovertebral junction & spineReview
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLower mortality has been demonstrated when vertebral compression fractures (VCFs) are treated surgically (vertebral augmentation) vs. conservatively.
aimsTo analyze the overall survival in patients over 65 who suffer a VCF, to review the principal causes of death, and to detect which factors are associated with a greater risk of mortality.
methodsPatients over 65 years old diagnosed with acute, non-pathologic thoracic or lumbar VCF, treated consecutively from January 2017 to December 2020, were retrospectively selected. Those patients with follow-ups under 2 years or who required arthrodesis were excluded. Overall survival was estimated by the Kaplan-Meier method. Differences in survival were tested through the log-rank test. Multivariable Cox regression was used to assess the association of covariates and time to death.
resultsA total of 492 cases were included. Overall mortality was 36.2%. Survival rate at 1-, 12-, 24-, 48-, and 60-month follow-up was 97.4%, 86.6%, 78.0%, 64.4%, and 59.4%, respectively. Infection was the leading cause of death. The independent factors associated with a higher mortality risk were age, male, oncologic history, non-traumatic mechanism, and comorbidity during hospitalization. No statistical difference was found when comparing the two survival curves by treatment (vertebral augmentation vs. conservative) over time.
conclusionOverall mortality rate was 36.2% after a median follow-up of 50.5 months (95% CI 48.2; 54.2). Age, male sex, history of oncological disease, non-traumatic mechanism of the fracture, and any comorbidity during hospitalization were identified as variables independently associated with a higher risk of mortality following a VCF in the elderly.
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