ArticleEsophagus : official journal of the Japan Esophageal Society2023
Impact of MRI on the post-therapeutic diagnosis of T4 esophageal cancer.
Article in Esophagus : official journal of the Japan Esophageal Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 8 citations in OpenAlex.
- Surgical technique for partial-layer tracheal resection for esophageal cancer with tracheal invasion.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- Refining the role of extended resection in multidisciplinary treatment for cT4b esophageal cancer.Journal of thoracic disease · 2026Article
- Review
- MRI outperforms CT for tracheal and vascular invasion staging in esophageal cancer.European radiology · 2026Article
- Evaluation of Changes in Squamous Cell Carcinoma Antigen Levels After Neoadjuvant Chemotherapy to Support Preoperative Diagnosis of Adjacent Organ Invasion in Locally Advanced Esophageal Squamous Cell Carcinoma.Annals of surgical oncology · 2026Article
- Conversion surgery following immunochemotherapy for initially unresectable/recurrent esophageal cancer.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- Clinical usefulness of four-dimensional dynamic ventilation CT for borderline resectable locally advanced esophageal cancer.Japanese journal of radiology · 2025Article
- Evaluation of Tracheobronchial Invasion as a Determinant of Treatment Strategy and Resectability in Locally Advanced Esophageal Cancer.Annals of surgical oncology · 2025Article
- Review of the Japanese Classification of Esophageal Cancer 12th Edition, and Proposals for the 13th Edition.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2024Review
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15 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundOpportunities for T4b esophageal cancer patients to receive curative surgery are increasing with the development of multidisciplinary treatments. However, the best modality to accurately diagnose infiltration to the organs surrounding T4b esophageal cancer is still unknown. The aim of this study was to determine the performance of CT and MRI in diagnosing T stage in T4b esophageal cancer, with reference to the pathological diagnosis.
methodsA retrospective medical records review of patients with T4b esophageal cancer patients from January 2017 to December 2021 was conducted. Among 125 patients who were treated for cT4b esophageal cancer in Osaka University Hospital, 30 patients were diagnosed with cT4b esophageal cancer by CT, ycT staging with CT (contrast-enhanced images) and MRI (T2-FSE images), and curative R0 resection was performed. Preoperative MRI staging was independently performed by two experienced radiologists. The diagnostic performance of CT and MRI were examined using McNemar's test.
resultsNineteen and 12 patients were diagnosed with ycT4b by CT and MRI, respectively. Combined T4b organ resection was performed in 15 patients. A pathological diagnosis of ypT4b was made in 11 cases. In comparison to CT, MRI showed a higher diagnostic performance, specificity (47% vs. 89%, p = 0.013), and accuracy (60% vs. 90%, p = 0.015) for CT vs. MRI.
conclusionsOur results-with reference to the pathological diagnosis-revealed that MRI had a superior diagnostic performance to CT for diagnosing T4b esophageal cancer invading the surrounding organs. An accurate diagnosis of T4b esophageal cancer may facilitate the implementation of appropriate treatment strategies.
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