ReviewMetabolites2023
The Role of Endocan in Cardiometabolic Disorders.
Review in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Expression profile of apolipoproteins (APOE) and endothelin-1 (ET-1) genes in ischemic heart disease.BMC cardiovascular disorders · 2026Article
- The Role of Endocan Level in Determining Large and Small Vessel Occlusion in Acute Ischemic Stroke.The Eurasian journal of medicine · 2026Article
- Syndecan-1, endocan and non-culprit coronary plaque composition following non-ST elevation myocardial infarction.International journal of cardiology. Heart & vasculature · 2026Article
- Correlation of Lp(a), ApoB and oxLDL with Endothelial Damage Reading in Patients with Different Degrees of Coronary Atherosclerosis.International journal of molecular sciences · 2026Article
- Diagnostic value of endothelial-specific molecule-1 levels in patients with bone tumors.Acta biochimica Polonica · 2026Article
- Synergistic Impact of Obesity and PCOS on Immune Dysregulation: A Review of Systemic and Local Inflammatory Profiles.International journal of women's health · 2026Review
- Vasculoprotective role of del Nido cardioplegia in open-heart surgery via modulation of E-Selectin, Endocan, and TNF-alpha coronary sinus blood samples.Journal of cardiothoracic surgery · 2025Article
- Assessment of Serum Endocan Levels and Their Associations with Arterial Stiffness Parameters in Young Patients with Systemic Lupus Erythematosus.Journal of clinical medicine · 2025Article
- Serum Endocan Levels Correlate with Metabolic Syndrome Severity and Endothelial Dysfunction: A Cross-Sectional Study Using the MetS-Z Score.Metabolites · 2025Article
- Serum endocan, asymmetric dimethylarginine and lipid profile in children with familial Mediterranean fever.Pediatric research · 2025Article
- Upper airway microcirculation remodeling in obstructive sleep apnea is not driven by endothelial activation.Scientific reports · 2025Article
- Association between oxidative balance score with cardiovascular - kidney - metabolic syndrome and all-cause mortality among US population.Frontiers in nutrition · 2025Article
- Biochemical markers and carotid intima-media thickness in relation to cardiovascular risk in young women.Scientific reports · 2024Article
- Cardiovascular Risk in Patients with Ankylosing Spondylitis.Journal of clinical medicine · 2024Article
- Protein glycosylation in cardiovascular health and disease.Nature reviews. Cardiology · 2024Review
- Exploring metabolically healthy obesity: prevalence, characteristics, and cardiovascular risk in the Iranian population based on the STEPS 2021.Journal of diabetes and metabolic disorders · 2024Article
- Relationship between angiogenesis biomarker endocan and apolipoproteins in patients with acute myocardial infarction.Future cardiology · 2024Article
- Endocan may predict the presence of coronary slow flow and coronary artery disease.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Cardiovascular-kidney-metabolic syndrome - An integrative review.Progress in cardiovascular diseasesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Discovered two decades ago, endocan still represents an intriguing biomarker related to inflammation. Endocan is a soluble dermatan sulphate proteoglycan secreted by endothelial cells. Its expression is observed in tissues related to the enhanced proliferation, especially hepatocytes, lungs, kidneys, etc. Endocan has been investigated in many cardiometabolic disorders that are tightly connected with inflammation, such as type 2 diabetes mellitus, hypertension, atherosclerotic cardiovascular disease, kidney disease, obesity, polycystic ovary syndrome, metabolic syndrome, non-alcoholic fatty liver disease, etc. In this narrative, comprehensive review of the currently available literature, special attention will be paid to the role of endocan in the broad spectrum of cardiometabolic disorders. Since endocan has emerged as a novel endothelial dysfunction marker, the discovery of potential therapeutic strategies for patients with certain cardiometabolic risk factors would be of great importance to delay or even prevent the onset and progression of related complications, mainly cardiovascular.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.