Evidence map›Paper›PMID 37233677›Full record

ArticleMetabolites2023

Cerebral Glutamate Alterations Using Chemical Exchange Saturation Transfer Imaging in a Rat Model of Lipopolysaccharide-Induced Sepsis.

Do-Wan Lee, Jae-Im Kwon, Hwon Heo, Chul-Woong Woo, Na Hee Yu, Kyung Won Kim, Dong-Cheol Woo

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Limited Contribution of TMolecular imaging and biology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. CEST MRI in the Management/Diagnosis of Neuroinfectious Diseases.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Do-Wan LeeDepartment of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Republic of Korea.ORCID 0000-0001-7925-0333
Jae-Im KwonDepartment of Medical Science, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Republic of Korea.
Hwon HeoDepartment of Convergence Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Republic of Korea.
Chul-Woong WooConvergence Medicine Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul 05505, Republic of Korea.
Na Hee YuNonclinical Research Center, QuBEST BIO Inc., Giheung-gu, Yongin-si 17015, Gyeonggi-do, Republic of Korea.
Kyung Won KimDepartment of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Republic of Korea.ORCID 0000-0002-1532-5970
Dong-Cheol WooDepartment of Medical Science, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Republic of Korea.
Ulsan College · KRAsan Medical Center · KR

Funding

Asan Institute for Life Sciences, Asan Medical Center 2020IL0014-1National Research Foundation of Korea (NRF) grant funded by the Korea Government (Ministry of Science and ICT, MSIT) NRF-2022R1C1C2008801
6 · The paper itself

Abstract

Glutamate-weighted chemical exchange saturation transfer (GluCEST) is a useful imaging tool to detect glutamate signal alterations caused by neuroinflammation. This study aimed to visualize and quantitatively evaluate hippocampal glutamate alterations in a rat model of sepsis-induced brain injury using GluCEST and proton magnetic resonance spectroscopy (

Indexed as

chemical exchange saturation transferglutamatelipopolysaccharidesepsis

Identifiers

PMID37233677
PMCPMC10224036
OpenAlexW4378349547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.