Evidence map›Paper›PMID 37233652›Full record

ArticleMetabolites2023

Application of Benchtop NMR for Metabolomics Study Using Feces of Mice with DSS-Induced Colitis.

Zihao Song, Yuki Ohnishi, Seiji Osada, Li Gan, Jiaxi Jiang, Zhiyan Hu, Hiroyuki Kumeta, Yasuhiro Kumaki, Yuki Yokoi, Kiminori Nakamura and 3 more

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zihao SongLaboratory of Protein Science, Graduate School of Life Science, Hokkaido University, Sapporo 060-0808, Japan.ORCID 0000-0003-4976-5832
Yuki OhnishiLaboratory of Protein Science, Graduate School of Life Science, Hokkaido University, Sapporo 060-0808, Japan.
Seiji OsadaNakayama Co., Ltd., Tsukuba 300-2651, Japan.
Li GanLaboratory of Protein Science, Graduate School of Life Science, Hokkaido University, Sapporo 060-0808, Japan.ORCID 0009-0002-7517-3478
Jiaxi JiangLaboratory of Protein Science, Graduate School of Life Science, Hokkaido University, Sapporo 060-0808, Japan.
Zhiyan HuLaboratory of Protein Science, Graduate School of Life Science, Hokkaido University, Sapporo 060-0808, Japan.
Hiroyuki KumetaAdvanced NMR Facility, Faculty of Advanced Life Science, Hokkaido University, Sapporo 060-0808, Japan.ORCID 0000-0003-3713-2122
Yasuhiro KumakiHigh-Resolution NMR Laboratory, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan.
Yuki YokoiInnate Immunity Laboratory, Graduate School of Life Science, Hokkaido University, Sapporo 060-0808, Japan.ORCID 0000-0002-8077-3200
Kiminori NakamuraInnate Immunity Laboratory, Graduate School of Life Science, Hokkaido University, Sapporo 060-0808, Japan.
Tokiyoshi AyabeInnate Immunity Laboratory, Graduate School of Life Science, Hokkaido University, Sapporo 060-0808, Japan.ORCID 0000-0002-8631-5593
Kazuo YamauchiInstrumental Analysis Section, Okinawa Institute of Science and Technology, Onna 904-0495, Japan.
Tomoyasu AizawaLaboratory of Protein Science, Graduate School of Life Science, Hokkaido University, Sapporo 060-0808, Japan.ORCID 0000-0001-9134-7576
Hokkaido University · JPOkinawa Institute of Science and Technology Graduate University · JP

Funding

Japan Society for the Promotion of Science JPMJCE1301Japan Society for the Promotion of Science JPMJPF2108Japan Society for the Promotion of Science JPMJSP2119
6 · The paper itself

Abstract

Nuclear magnetic resonance (NMR)-based metabolomics, which comprehensively measures metabolites in biological systems and investigates their response to various perturbations, is widely used in research to identify biomarkers and investigate the pathogenesis of underlying diseases. However, further applications of high-field superconducting NMR for medical purposes and field research are restricted by its high cost and low accessibility. In this study, we applied a low-field, benchtop NMR spectrometer (60 MHz) employing a permanent magnet to characterize the alterations in the metabolic profile of fecal extracts obtained from dextran sodium sulfate (DSS)-induced ulcerative colitis model mice and compared them with the data acquired from high-field NMR (800 MHz). Nineteen metabolites were assigned to the 60 MHz

Indexed as

benchtop NMRDSS-induced micefecesmetabolomics

Identifiers

PMID37233652
PMCPMC10224185
OpenAlexW4367310233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.