Evidence map›Paper›PMID 37233641›Full record

ArticleMetabolites2023

Application of Lipidomics in Psychiatry: Plasma-Based Potential Biomarkers in Schizophrenia and Bipolar Disorder.

Alana C Costa, Larissa B Riça, Martinus van de Bilt, Flávia S Zandonadi, Wagner F Gattaz, Leda L Talib, Alessandra Sussulini

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Biomarkers of bipolar disorder in omics and neuroimaging.Journal of pharmaceutical analysis · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. LC-HRMS Lipidomic Fingerprints in Serbian Cohort of Schizophrenia Patients.International journal of molecular sciences · 2024
    Article
  11. Multi Omics Applications in Biological Systems.Current issues in molecular biology · 2024
    Review
  12. Review
  13. Untargeted Lipidomics Study of Bipolar Disorder Patients in Serbia.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alana C CostaLaboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, University of Sao Paulo Medical School, Sao Paulo 05403903, Brazil.ORCID 0000-0002-9832-5860
Larissa B RiçaLaboratory of Bioanalytics and Integrated Omics (LaBIOmics), Institute of Chemistry, University of Campinas (UNICAMP), Campinas 13083970, Brazil.ORCID 0000-0001-5702-9312
Martinus van de BiltLaboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, University of Sao Paulo Medical School, Sao Paulo 05403903, Brazil.
Flávia S ZandonadiLaboratory of Bioanalytics and Integrated Omics (LaBIOmics), Institute of Chemistry, University of Campinas (UNICAMP), Campinas 13083970, Brazil.ORCID 0000-0002-5166-6019
Wagner F GattazLaboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, University of Sao Paulo Medical School, Sao Paulo 05403903, Brazil.
Leda L TalibLaboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, University of Sao Paulo Medical School, Sao Paulo 05403903, Brazil.ORCID 0000-0001-5866-1993
Alessandra SussuliniLaboratory of Bioanalytics and Integrated Omics (LaBIOmics), Institute of Chemistry, University of Campinas (UNICAMP), Campinas 13083970, Brazil.ORCID 0000-0002-5092-5867
National Council for Scientific and Technological Development · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

São Paulo Research Foundation 2014/50867-3São Paulo Research Foundation 2014/50873-3São Paulo Research Foundation 2017/26291-2São Paulo Research Foundation 2018/01525-3
6 · The paper itself

Abstract

In this study, we obtained a lipidomic profile of plasma samples from drug-naïve patients with schizophrenia (SZ) and bipolar disorder (BD) in comparison to healthy controls. The sample cohort consisted of 30 BD and 30 SZ patients and 30 control individuals. An untargeted lipidomics strategy using liquid chromatography coupled with high-resolution mass spectrometry was employed to obtain the lipid profiles. Data were preprocessed, then univariate (

Indexed as

biomarkersbipolar disorderlipidomicsplasmaschizophrenia

Identifiers

PMID37233641
PMCPMC10222421
OpenAlexW4367181572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.