Evidence map›Paper›PMID 37233493›Full record

ReviewMarine drugs2023

Extraction, Modification and Biomedical Application of Agarose Hydrogels: A Review.

Feng Jiang, Xin-Wei Xu, Fu-Quan Chen, Hui-Fen Weng, Jun Chen, Yi Ru, Qiong Xiao, An-Feng Xiao

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
39.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 115 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Sprayable Hydrogel Dressings in Wound-Healing Applications.Bioengineering (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Novel NTA-NiPolymers · 2026
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Feng JiangCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China.
Xin-Wei XuCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China.
Fu-Quan ChenCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China.
Hui-Fen WengCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China.
Jun ChenCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China.
Yi RuCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China.
Qiong XiaoCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China.ORCID 0000-0001-9470-3927
An-Feng XiaoCollege of Ocean Food and Biological Engineering, Jimei University, Xiamen 361021, China.ORCID 0000-0003-0327-8860
Jimei University · CN

Funding

Fujian Province Science and Technology Association 2022J01805National Natural Science Foundation of China 22278173National Natural Science Foundation of China 32201941
6 · The paper itself

Abstract

Numerous compounds present in the ocean are contributing to the development of the biomedical field. Agarose, a polysaccharide derived from marine red algae, plays a vital role in biomedical applications because of its reversible temperature-sensitive gelling behavior, excellent mechanical properties, and high biological activity. Natural agarose hydrogel has a single structural composition that prevents it from adapting to complex biological environments. Therefore, agarose can be developed into different forms through physical, biological, and chemical modifications, enabling it to perform optimally in different environments. Agarose biomaterials are being increasingly used for isolation, purification, drug delivery, and tissue engineering, but most are still far from clinical approval. This review classifies and discusses the preparation, modification, and biomedical applications of agarose, focusing on its applications in isolation and purification, wound dressings, drug delivery, tissue engineering, and 3D printing. In addition, it attempts to address the opportunities and challenges associated with the future development of agarose-based biomaterials in the biomedical field. It should help to rationalize the selection of the most suitable functionalized agarose hydrogels for specific applications in the biomedical industry.

Indexed as

Biocompatible MaterialsHydrogelsDrug Delivery SystemsSepharoseTissue EngineeringBiocompatible MaterialsHydrogelsSepharoseagarosebiomedical applicationhydrogelmodification

Identifiers

PMID37233493
PMCPMC10220669
OpenAlexW4378348527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.