Evidence map›Paper›PMID 37233489›Full record

ArticleMarine drugs2023

A Screening Approach to Assess the Impact of Various Commercial Sources of Crude Marine λ-Carrageenan on the Production of Oligosaccharides with Anti-heparanase and Anti-migratory Activities.

Chanez Manseur, Hugo Groult, Manon Porta, Pierre-Edouard Bodet, Rachida Mersni-Achour, Raphaëlle Petit, Samir Ali-Moussa, Benjamin Musnier, Didier Le Cerf, Tony Varacavoudin and 8 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Chanez ManseurUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.ORCID 0009-0009-8499-0198
Hugo GroultUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.ORCID 0000-0002-1571-9400
Manon PortaUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.
Pierre-Edouard BodetUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.ORCID 0000-0003-1904-4823
Rachida Mersni-AchourUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.
Raphaëlle PetitUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.ORCID 0000-0002-0405-3180
Samir Ali-MoussaUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.
Benjamin MusnierUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.
Didier Le CerfSciences & Technic Faculty, Univ Rouen Normandie, INSA Rouen Normandie, CNRS, PBS UMR 6270, 76000 Rouen, France.ORCID 0000-0001-9537-8003
Tony VaracavoudinSciences & Technic Faculty, Univ Rouen Normandie, INSA Rouen Normandie, CNRS, PBS UMR 6270, 76000 Rouen, France.
Oualid HaddadInserm U1148, Laboratory for Vascular Translational Science, UFR SMBH, Université Paris 13, Sorbonne Paris Cité, Groupe Biothérapies et Glycoconjugués, 93000 Bobigny, France.
Angela SuttonInserm U1148, Laboratory for Vascular Translational Science, UFR SMBH, Université Paris 13, Sorbonne Paris Cité, Groupe Biothérapies et Glycoconjugués, 93000 Bobigny, France.
Cíntia Emi Yanaguibashi LealCollege of Pharmaceutical Sciences, Federal University of Vale do São Francisco (UNIVASF), Petrolina 56304-205, PE, Brazil.
Edilson Beserra Alencar-FilhoCollege of Pharmaceutical Sciences, Federal University of Vale do São Francisco (UNIVASF), Petrolina 56304-205, PE, Brazil.ORCID 0000-0002-1000-0114
Jean-Marie PiotUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.
Nicolas BridiauUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.ORCID 0000-0003-1839-9286
Thierry MaugardUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.ORCID 0000-0002-9196-7780
Ingrid Fruitier-ArnaudinUMR CNRS 7266, LIENSs Laboratory, La Rochelle University, 17000 La Rochelle, France.
Centre National de la Recherche Scientifique · FRInserm · FRUniversidade Federal do Vale do São Francisco · BR

Funding

Agence Nationale de la Recherche NANOLIGOConseil Régional de Nouvelle-Aquitaine MOLNATConseil Régional de Nouvelle-Aquitaine NANOVECTLigue contre le cancer CD16 2021-2023LIgue contre le cancer CD17 2021-2023
6 · The paper itself

Abstract

Oligosaccharides derived from λ-carrageenan (λ-COs) are gaining interest in the cancer field. They have been recently reported to regulate heparanase (HPSE) activity, a protumor enzyme involved in cancer cell migration and invasion, making them very promising molecules for new therapeutic applications. However, one of the specific features of commercial λ-carrageenan (λ-CAR) is that they are heterogeneous mixtures of different CAR families, and are named according to the thickening-purpose final-product viscosity which does not reflect the real composition. Consequently, this can limit their use in a clinical applications. To address this issue, six commercial λ-CARs were compared and differences in their physiochemical properties were analyzed and shown. Then, a H

Indexed as

Hydrogen PeroxideNeoplasmsCarrageenanHumansOligosaccharidesCarrageenanHydrogen PeroxideOligosaccharidesanticancer agentsheparanaselambda-carrageenanmarine algaemigrationoligosaccharides

Identifiers

PMID37233489
PMCPMC10221831
OpenAlexW4378348631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.