Evidence map›Paper›PMID 37233159›Full record

ArticleJournal of cardiovascular development and disease2023

Transcatheter Aortic Valve Replacement Prognostication with Augmented Mean Arterial Pressure.

Chieh-Ju Chao, Pradyumna Agasthi, Amith R Seri, Timothy Barry, Anusha Shanbhag, Yuxiang Wang, Mackram F Eleid, David Fortuin, John P Sweeney, Peter Pollak and 7 more

Abstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Chieh-Ju ChaoDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
Pradyumna AgasthiDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
Amith R SeriDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
Timothy BarryDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.ORCID 0000-0002-0576-2990
Anusha ShanbhagDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
Yuxiang WangDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
Mackram F EleidDepartment of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN 55905, USA.
David FortuinDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
John P SweeneyDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
Peter PollakDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Abdallah El SabbaghDepartment of Cardiovascular Diseases, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Steven J LesterDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
William K FreemanDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
Tasneem Z NaqviDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
David R HolmesDepartment of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN 55905, USA.
Christopher P AppletonDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.
Reza ArsanjaniDepartment of Cardiovascular Diseases, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.ORCID 0000-0001-7081-4286

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-transcatheter aortic valve replacement (TAVR) patient outcome is an important research topic. To accurately assess post-TAVR mortality, we examined a family of new echo parameters (augmented systolic blood pressure (AugSBP) and arterial mean pressure (AugMAP)) derived from blood pressure and aortic valve gradients.

methodsPatients in the Mayo Clinic National Cardiovascular Diseases Registry-TAVR database who underwent TAVR between 1 January 2012 and 30 June 2017 were identified to retrieve baseline clinical, echocardiographic and mortality data. AugSBP, AugMAP and valvulo-arterial impedance (Zva) (Zva) were evaluated using Cox regression. Receiver operating characteristic curve analysis and the c-index were used to assess the model performance against the Society of Thoracic Surgeons (STS) risk score.

resultsThe final cohort contained 974 patients with a mean age of 81.4 ± 8.3 years old, and 56.6% were male. The mean STS risk score was 8.2 ± 5.2. The median follow-up duration was 354 days, and the one-year all-cause mortality rate was 14.2%. Both univariate and multivariate Cox regression showed that AugSBP and AugMAP parameters were independent predictors for intermediate-term post-TAVR mortality (all

conclusionsAugmented mean arterial pressure provides clinicians with a simple but effective approach to quickly identify patients at risk and potentially improve post-TAVR prognosis.

Indexed as

aortic valve stenosisaugmented mean arterial pressuremortalitySTS risk scoretranscatheter aortic valve replacement (TAVR)

Identifiers

PMID37233159
PMCPMC10218897

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.