Evidence map›Paper›PMID 37233005›Full record

ArticleGels (Basel, Switzerland)2023

Optimal Concentration and Duration of Endotracheal Tube Coating to Achieve Optimal Antimicrobial Efficacy and Safety Balance: An In Vitro Study.

Manar Fathy Al-Sayed, Mohamed Tarek El-Wakad, Mohammed A Hassan, Ahmed M Soliman, Amal S Eldesoky

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Manar Fathy Al-SayedDepartment of Biomedical Engineering, Faculty of Engineering, Helwan University, Cairo 11511, Egypt.ORCID 0009-0002-0530-8701
Mohamed Tarek El-WakadFaculty of Engineering & Technology, Future University, Cairo 11835, Egypt.ORCID 0000-0003-2637-1048
Mohammed A HassanDepartment of Biomedical Engineering, Faculty of Engineering, Helwan University, Cairo 11511, Egypt.
Ahmed M SolimanDepartment of Biomedical Engineering, Faculty of Engineering, Helwan University, Cairo 11511, Egypt.ORCID 0000-0002-8901-8519
Amal S EldesokyDepartment of Biomedical Engineering, Higher Technological Institute, Cairo 11511, Egypt.
Helwan University · EGHigher Technological Institute · EGFuture University in Egypt · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVentilator-associated pneumonia (VAP) is a common and genuine complication in fundamentally sick patients accepting mechanical ventilation. Silver nitrate sol-gel (SN) has been proposed as a potential preventative measure against VAP. Be that as it may, the arrangement of SN with distinctive concentrations and pH values remains a basic factor influencing its effectiveness.

methodsSilver nitrate sol-gel was arranged with distinctive concentrations (0.1852%, 0.03496%, 0.1852%, and 0.01968%) and pH values (8.5, 7.0, 8.0, and 5.0) separately. The antimicrobial action of the silver nitrate and NaOH arrangements were assessed against

resultsThe pH estimations of the diverse arrangements showed that the pH values shifted depending on the test conditions, with pH values extending from 5.0 to 8.5. The consistency estimations of the arrangements showed that the thickness values expanded as the pH values drew closer to 7.5 and diminished when the pH values went over 7.5. The antimicrobial action of the silver nitrate and NaOH arrangements were successful against

conclusionsWe propose that cautious control and alteration of the pH and thickness of the arrangements are essential to guaranteeing the reproducibility and quality of the sol-gel materials. The silver nitrate and NaOH arrangements may serve as a potential preventative degree against VAP in sick patients, with a concentration of 0.03496% appearing to show the most elevated viability. The coating tube may serve as a secure and viable preventative measure against VAP in sick patients. Further investigation is required to optimize the concentration and introduction time of the arrangements to maximize their adequacy in avoiding VAP in real-world clinical settings.

Indexed as

antibioticsantifungalsantimicrobial agentsantimicrobial efficacyantisepticsbacteria proliferationbiocompatibleendotracheal intubationendotracheal tubemechanical ventilationsilver nitrate sol-geltoxicityventilator-associated pneumonia

Identifiers

PMID37233005
PMCPMC10217730
OpenAlexW4376644086

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.