ArticleGels (Basel, Switzerland)2023
Formulation Development and Evaluation of Indian Propolis Hydrogel for Wound Healing.
Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Redox-Regulating Propolis- and Honey-Containing Hydrogels in Osteoarthritis.Antioxidants (Basel, Switzerland) · 2026Review
- Article
- Wound-Healing Effects of Birch Bark and Propolis Extracts on Epidermolysis Bullosa Keratinocytes.International journal of molecular sciences · 2026Article
- Formulation and evaluation of hydrogel based on Brazilian propolis ethanol extract for promoting diabetic wound healing.BMC biotechnology · 2026Article
- Thermoresponsive propolis gel for gingival wound healing post-depigmentation: A prospective clinical study.Journal of Taibah University Medical Sciences · 2026Article
- Natural Compound-Loaded PLGA Nanocarriers for Infected Wound Management: A Review.International journal of nanomedicine · 2026Review
- Propolis Stands out as a Multifaceted Natural Product: Meta-Analysis on Its Sources, Bioactivities, Applications, and Future Perspectives.Life (Basel, Switzerland) · 2025Review
- Antimicrobial Properties of Hive Products and Their Potential Applications in Human and Veterinary Medicine.Antibiotics (Basel, Switzerland) · 2025Review
- Electrically conductive "SMART" hydrogels for on-demand drug delivery.Asian journal of pharmaceutical sciences · 2025Review
- Article
- Carbopol 940-based hydrogels loading synergistic combination of quercetin and luteolin from the herbRSC medicinal chemistry · 2024Article
- Effect of Mexican Propolis on Wound Healing in a Murine Model of Diabetes Mellitus.International journal of molecular sciences · 2024Article
- Applications of propolis-based materials in wound healing.Archives of dermatological research · 2023Review
- Anti-Inflammatory and Histological Analysis of Skin Wound Healing through Topical Application of Mexican Propolis.International journal of molecular sciences · 2023Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Flavonoids and polyphenolic compounds play a key role in wound healing cycle modulation. Propolis, a natural bee product, has been widely reported as an enriched source of polyphenols and flavonoids as important chemical constituents and for its wound healing potential. The goal of this study was to develop and characterize a propolis-based polyvinyl alcohol (PVA) hydrogel composition with wound healing potential. To understand the impacts of critical material attributes and process parameters, formulation development was carried out using a design of experiment approach. A preliminary phytochemical analysis of Indian propolis extract showed the presence of flavonoids (23.61 ± 0.0452 mg equivalent of quercetin/g) and polyphenols (34.82 ± 0.0785 mg equivalent of gallic acid/g), both of which aid in wound healing and skin tissue regeneration. The pH, viscosity, and in vitro release of the hydrogel formulation were also studied. The burn wound healing model results revealed significant (
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