Evidence map›Paper›PMID 37232897›Full record

ArticleBiosensors2023

Enhanced Competitive Immunomagnetic Beads Assay Assisted with PAMAM-Gold Nanoparticles Multi-Enzyme Probes for Detection of Deoxynivalenol.

Kun Zeng, Jian Yang, Hao Su, Sheng Yang, Xinkai Gu, Zhen Zhang, Hongjun Zhao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. MOF-engineered CuMikrochimica acta · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kun ZengSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China.
Jian YangSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China.
Hao SuSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China.
Sheng YangSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China.
Xinkai GuSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China.
Zhen ZhangSchool of the Environment and Safety Engineering, Jiangsu University, Zhenjiang 212013, China.
Hongjun ZhaoDepartment of Pulmonary and Critical Care Medicine, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, 100 Minjiang Ave, Quzhou 324000, China.ORCID 0000-0002-9999-7220
Jiangsu University · CNWenzhou Medical University · CN

Funding

Jiangsu Agricultural Science and Technology Innovation Fund CX (21)3173Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment 0Quzhou High-level medical and health talents program KYQD2022-26
6 · The paper itself

Abstract

Contamination of deoxynivalenol (DON) in grains has attracted widespread concern. It is urgently needed to develop a highly sensitive and robust assay for DON high-throughput screening. Antibody against DON was assembled on the surface of immunomagnetic beads orientationally by the aid of Protein G. AuNPs were obtained under the scaffolding of poly(amidoamine) dendrimer (PAMAM). DON-horseradish peroxidase (HRP) was combined on the periphery of AuNPs/PAMAM by a covalent link to develop DON-HRP/AuNPs/PAMAM. Magnetic immunoassay based on DON-HRP/AuNPs/PAMAM was optimized and that based on DON-HRP/AuNPs and DON-HRP was adopted as comparison. The limits of detection (LODs) were 0.447 ng/mL, 0.127 ng/mL and 0.035 ng/mL for magnetic immunoassays based on DON-HRP, DON-HRP/Au and DON-HRP/Au/PAMAM, respectively. Magnetic immunoassay based on DON-HRP/AuNPs/PAMAM displayed higher specificity towards DON and was utilized to analyze grain samples. The recovery for the spiked DON in grain samples was 90.8-116.2% and the method presented a good correlation with UPLC/MS. It was found that the concentration of DON was in the range of ND-3.76 ng/mL. This method allows the integration of dendrimer-inorganic NPs with signal amplification properties for applications in food safety analysis.

Indexed as

Biosensing TechniquesDendrimersMetal NanoparticlesGoldHorseradish PeroxidaseImmunoassayTrichothecenesDendrimersdeoxynivalenolGoldHorseradish PeroxidaseTrichothecenesdeoxynivalenolgold nanoparticlesmulti-enzyme probesPAMAM

Identifiers

PMID37232897
PMCPMC10216259
OpenAlexW4378349176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.