Evidence map›Paper›PMID 37232768›Full record

ArticleDentistry journal2023

An International Investigation of Molar Incisor Hypomineralisation (iMIH) and Its Association with Dental Anomalies: Development of a Protocol.

Helen D Rodd, Hani Nazzal, Clarissa Calil Bonifacio, Choe Wei Ruth, Felicity Crombie, Osama El Shahawy, Morenike Oluwatoyin Folayan, Karla Gambetta-Tessini, Ashima Goyal, Noren Hasmun and 10 more

Open access · goldAbstract read
In one paragraph

Article in Dentistry journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Causal effect of molar incisor hypomineralisation on oral health-related quality of life of Australian children aged 7-16 years.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  2. Association between molar incisor hypomineralisation and tooth agenesis: a cross-sectional study in Brazilian children and adolescents.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 19 institutions in 13 countries.

Helen D RoddUnit of Oral Health, Dentistry and Society, School of Clinical Dentistry, University of Sheffield, Sheffield S10 2TA, UK.ORCID 0000-0003-2973-2558
Hani NazzalDepartment Clinical Oral Health Sciences, College of Dental Medicine, Qatar University, Doha P.O. Box 2713, Qatar.
Clarissa Calil BonifacioAcademic Center for Dentistry (ACTA), Gustav Mahlerlaan, 3004 Amsterdam, The Netherlands.ORCID 0000-0001-6515-2927
Choe Wei RuthNational University Centre for Oral Health Singapore, Singapore 119085, Singapore.
Felicity CrombieMelbourne Dental School, University of Melbourne, Melbourne 3010, Australia.
Osama El ShahawyPediatric Dentistry Department, Cairo University, Cairo 12613, Egypt.
Morenike Oluwatoyin FolayanDepartment of Child Dental Health, Obafemi Awolowo University, Ile-Ife 22005, Nigeria.ORCID 0000-0002-9008-7730
Karla Gambetta-TessiniDepartment of Oral Rehabilitation, Faculty of Dentistry, University of Talca, Talca 3460000, Maule, Chile.
Ashima GoyalOral Health Sciences Centre, PGIMER, Chandigarh 160012, India.
Noren HasmunDepartment of Oral Sciences, Faculty of Dentistry, University of Otago, Dunedin 9054, New Zealand.ORCID 0000-0002-4279-4123
Ahmad I IssaMinistry of National Guard Health Affairs, King Abdulaziz Hospital, Riyadh 36428, Al Ahsa, Saudi Arabia.
Suhad JundiPreventive Dentistry Department, Faculty of Dentistry, Jordan University of Science and Technology, Ar-Ramtha P.O. Box 3030, Jordan.
David J MantonAcademic Center for Dentistry (ACTA), Gustav Mahlerlaan, 3004 Amsterdam, The Netherlands.ORCID 0000-0002-4570-0620
Srinivasan NarasimhanHamad Dental Centre, Hamad, Medical Corporation, Doha P.O. Box 3050, Qatar.
Samah OmarPediatric Dentistry Department, Loma Linda University School of Dentistry, Loma Linda, CA 92350, USA.
Susan ParekhUCL Eastman Dental Institute, London WC1E 6DG, UK.
Bamidele O PopoolaUniversity College Hospital, Agodi, Ibadan 200285, Nigeria.ORCID 0000-0003-2037-9698
Mihiri SilvaMelbourne Dental School, University of Melbourne, Melbourne 3010, Australia.
Greig TaylorSchool of Dental Sciences, Faculty of Medical Sciences, Newcastle University, Newcastle-upon-Tyne NE2 4AZ, UK.ORCID 0000-0001-9369-917X
Yang Qiyue NaomiYouth Preventive Services, Health Promotion Board, Singapore 179369, Singapore.
Hamad Medical Corporation · QAAcademic Center for Dentistry Amsterdam · NLCairo University · EGEastman Dental Hospital · GBHealth Promotion Board · SGJordan University of Science and Technology · JOKing Abdulaziz Hospital · SALoma Linda University · USNational University Health System · SGNewcastle University · GBObafemi Awolowo University · NGPost Graduate Institute of Medical Education and Research · INRoyal Children's Hospital · AUThe University of Melbourne · AUUniversity College Hospital, Ibadan · NGUniversity Medical Center Groningen · NLUniversity of Otago · NZUniversity of Sheffield · GBUniversity of Talca · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMolar incisor hypomineralisation (MIH) is a common disorder of tooth development, which has recently been found to be associated with a higher prevalence of hypodontia. The aim of this international multicentre study is to determine the association between MIH and other developmental anomalies in different populations.

methodsInvestigators were trained and calibrated for the assessment of MIH and dental anomalies and ethical approvals obtained in each participating country. The study aimed to recruit 584 children with MIH and 584 children without MIH. Patients aged 7-16 years who attend specialist clinics will be invited to participate. Children will undergo a clinical examination to determine the presence and severity of MIH, using an established index. The presence of any other anomalies, affecting tooth number, morphology, or position, will be documented. Panoramic radiographs will be assessed for dental anomalies and the presence of third permanent molars. Statistical analysis, using a chi squared test and regression analysis, will be performed to determine any differences in dental anomaly prevalence between the MIH and non-MIH group and to determine any association between dental anomalies and patient characteristics.

conclusionThis large-scale study has the potential to improve understanding about MIH with benefits for patient management.

Indexed as

dental anomalieshypodontiaMIH indexmolar hypomineralisationmolar incisor hypomineralisationprotocoltaurodontism

Identifiers

PMID37232768
PMCPMC10217515
OpenAlexW4367311020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.