Evidence map›Paper›PMID 37232746›Full record

ArticleCurrent issues in molecular biology2023

Clinicopathological Characteristics and Mutational Landscape of

Felix Manirakiza, Eric Rutaganda, Hidetaka Yamada, Yuji Iwashita, Belson Rugwizangoga, Benoit Seminega, Vincent Dusabejambo, Gervais Ntakirutimana, Deogratias Ruhangaza, Annette Uwineza and 2 more

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. The spectrum of TP53 mutations in Rwandan patients with gastric cancer.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Felix ManirakizaDepartment of Pathology, College of Medicine and Health Sciences, University of Rwanda, Kigali P.O. Box 3286, Rwanda.
Eric RutagandaDepartment of Internal Medicine, University Teaching Hospital of Kigali, Kigali P.O. Box 655, Rwanda.ORCID 0000-0002-5863-7026
Hidetaka YamadaDepartment of Tumor Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Shizuoka 431-3192, Japan.
Yuji IwashitaDepartment of Tumor Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Shizuoka 431-3192, Japan.ORCID 0000-0002-9085-5429
Belson RugwizangogaDepartment of Pathology, College of Medicine and Health Sciences, University of Rwanda, Kigali P.O. Box 3286, Rwanda.ORCID 0000-0001-6941-7320
Benoit SeminegaDepartment of Internal Medicine, University Teaching Hospital of Kigali, Kigali P.O. Box 655, Rwanda.
Vincent DusabejamboDepartment of Internal Medicine, University Teaching Hospital of Kigali, Kigali P.O. Box 655, Rwanda.
Gervais NtakirutimanaDepartment of Pathology, University Teaching Hospital of Kigali, Kigali P.O. Box 655, Rwanda.
Deogratias RuhangazaDepartment of Pathology, Butaro Hospital, Musanze P.O. Box 59, Rwanda.
Annette UwinezaDepartment of Pathology, University Teaching Hospital of Kigali, Kigali P.O. Box 655, Rwanda.
Kazuya ShinmuraDepartment of Tumor Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Shizuoka 431-3192, Japan.
Haruhiko SugimuraDepartment of Tumor Pathology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Shizuoka 431-3192, Japan.ORCID 0000-0002-0779-3088
Centre Hospitalier Universitaire de Kigali · RWHamamatsu University School of Medicine · JPSasaki Institute · JPUniversity of Kigali · RWUniversity of Rwanda · RWUniversity Teaching Hospital of Butare · RW

Funding

Japan Society for the Promotion of Science 22H04979SECOM Science and Technology Foundation 1-11-1Smoking Research Foundation 2019T009
6 · The paper itself

Abstract

Cancer research in Rwanda is estimated to be less than 1% of the total African cancer research output with limited research on colorectal cancer (CRC). Rwandan patients with CRC are young, with more females being affected than males, and most patients present with advanced disease. Considering the paucity of oncological genetic studies in this population, we investigated the mutational status of CRC tissues, focusing on the

Indexed as

AfricanAPCcolorectal cancergeneticsHOXB13KRASmutationpolyposis syndromeRwanda

Identifiers

PMID37232746
PMCPMC10217012
OpenAlexW4377104273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.